Protein: CDC42
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)

Gene: CDC42
Organism: Mus musculus
Interactions: 32
UniProt ID: P60766

Gene Ontology (top 5):
GO:0000322 - storage vacuole
GO:0003015 - heart process
GO:0003161 - cardiac conduction system development
GO:0003253 - cardiac neural crest cell migration involved in outflow tract morphogenesis
GO:0003924 - GTPase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

312739

PAK1
Serine/threonine-protein kinase PAK 1

3

20

Small-scale

0.821

High

953800

AGAP2
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2

1

20

High-throughput

0.691

High

953809

PK3CB
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform

1

20

Small-scale

0.665

High

953801

RHG01
Rho GTPase-activating protein 1

1

20

Small-scale

0.647

High

953808

RHG32
Rho GTPase-activating protein 32

1

20

Small-scale

0.647

High

59255

DOC11
Dedicator of cytokinesis protein 11

1

20

Small-scale

0.618

High

109224

G5E884
non-specific serine/threonine protein kinase

1

20

Small-scale

0.618

High

878597

CTRO
Citron Rho-interacting kinase

1

20

Small-scale

0.618

High

953802

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

9

Small-scale

0.618

High

953805

NEB2
Neurabin-2

1

20

High-throughput

0.618

High

953807

RHG33
Rho GTPase-activating protein 33

1

20

Small-scale

0.618

High

953810

DOC10
Dedicator of cytokinesis protein 10

1

20

Small-scale

0.618

High

953811

SRGP1
SLIT-ROBO Rho GTPase-activating protein 1

1

20

Small-scale

0.618

High

953814

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

20

Small-scale

0.618

High

953795

RAC1
Ras-related C3 botulinum toxin substrate 1

1

17

High-throughput

0.590

High

953798

RGS14
Regulator of G-protein signaling 14

1

0

High-throughput

0.586

High

953804

KPCI
Protein kinase C iota type

1

20

Small-scale

0.575

High

953813

PAR6B
Partitioning defective 6 homolog beta

1

20

Small-scale

0.575

High

107030

F8VPN7
Dedicator of cytokinesis 9

1

20

Small-scale

0.553

High

97382

PRRT2
Proline-rich transmembrane protein 2

1

20

High-throughput

0.479

High

147748

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

6

High-throughput

0.479

High

313337

COR1A
Coronin-1A

1

6

High-throughput

0.479

High

723307

SSR3
Somatostatin receptor type 3

1

11

High-throughput

0.479

High

953796

LIS1
Platelet-activating factor acetylhydrolase IB subunit beta

1

4

Small-scale

0.479

High

953797

VAMP2
Vesicle-associated membrane protein 2

1

20

Small-scale

0.479

High

953799

NMDE2
Glutamate receptor ionotropic, NMDA 2B

1

4

High-throughput

0.479

High

953803

SC6A4
Sodium-dependent serotonin transporter

1

20

High-throughput

0.479

High

953806

FACD2
Fanconi anemia group D2 protein homolog

1

6

High-throughput

0.479

High

953812

RBCC1
RB1-inducible coiled-coil protein 1

1

20

Small-scale

0.479

High

953815

HOME2
Homer protein homolog 2

1

20

Small-scale

0.479

High

915506

HMGA2
High mobility group protein HMGI-C

1

1

High-throughput

0.445

High

604510

SPI1
Transcription factor PU.1

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025