HitPredict

Interactor 1: CHD8 (Q09XV5)
Chromodomain-helicase-DNA-binding protein 8 (CHD-8) (EC 3.6.4.12) (ATP-dependent helicase CHD8) (Axis duplication inhibitor) (Duplin)
Gene: CHD8

Interactor 2: IMA5 (Q60960)
Importin subunit alpha-5 (Importin alpha-S1) (Karyopherin subunit alpha-1) (Nucleoprotein interactor 1) (NPI-1) (RAG cohort protein 2) (SRP1-beta)
Gene: Kpna1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	11744694
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2582 Mm			1 538
+	Mm
		192636 CHD8_MOUSE (1-2582): 0: 2401: 100.00		IMA4_MOUSE (1-538): 4.01e-144: 426: 45.66
+	Mm
		853539 CHD8_MOUSE (1-2582): 0: 2401: 100.00		IMA1_MOUSE (1-538): 7.03e-142: 421: 44.69
+	Hs
		238743 CHD8_HUMAN (1-2582): 0: 2363: 95.67		IMA7_HUMAN (1-538): 8.35e-156: 457: 80.30
+	Hs
		853720 CHD8_HUMAN (1-2582): 0: 2363: 95.67		IMA5_HUMAN (1-538): 3.65e-153: 450: 97.77
+	Hs
		168673 CHD8_HUMAN (1-2582): 0: 2363: 95.67		IMA6_HUMAN (1-538): 2.88e-147: 435: 79.37
+	Hs
		134969 CHD8_HUMAN (1-2582): 0: 2363: 95.67		IMA3_HUMAN (1-538): 3.5e-145: 429: 46.58
+	Hs
		853480 CHD8_HUMAN (1-2582): 0: 2363: 95.67		IMA1_HUMAN (1-538): 6.8e-144: 426: 44.51
+	Hs
		853580 CHD3_HUMAN (399-2065): 0: 1009: 23.47		IMA5_HUMAN (1-538): 3.65e-153: 450: 97.77
+	Hs
		853257 CHD3_HUMAN (399-2065): 0: 1009: 23.47		IMA1_HUMAN (1-538): 6.8e-144: 426: 44.51
+	Hs
		131423 CHD3_HUMAN (399-2065): 0: 1009: 23.47		IMA4_HUMAN (1-538): 2.37e-143: 424: 45.66
+	Hs
		229344 SMCA5_HUMAN (689-1724): 0: 873: 26.72		IMA5_HUMAN (1-538): 3.65e-153: 450: 97.77
+	Dm
		283986 CHDM_DROME (411-2065): 0: 893: 22.24		O76522_DROME (7-538): 1.01e-139: 415: 44.93
+	Hs
		658643 SMCA1_HUMAN (654-1705): 0: 858: 26.04		IMA5_HUMAN (1-538): 3.65e-153: 450: 97.77
+	Zm
		11289 A0A1D6IBX9_MAIZE (534-1453): 0: 807: 33.76		A0A1D6FC42_MAIZE (1-538): 3.6e-152: 447: 51.19
+	Zm
		12493 A0A1D6IBX9_MAIZE (534-1453): 0: 807: 33.76		A0A1D6FMC0_MAIZE (1-538): 1.46e-150: 445: 47.89
+	Hs
		846902 SMCA4_HUMAN (69-1480): 0: 788: 23.06		IMA5_HUMAN (1-538): 3.65e-153: 450: 97.77
+	Hs
		853716 Q9HBD4_HUMAN (69-1436): 0: 787: 23.35		IMA5_HUMAN (1-538): 3.65e-153: 450: 97.77
+	Hs
		846901 SMCA4_HUMAN (69-1480): 0: 788: 23.06		IMA1_HUMAN (1-538): 6.8e-144: 426: 44.51
+	Hs
		131405 SMCA4_HUMAN (69-1480): 0: 788: 23.06		IMA4_HUMAN (1-538): 2.37e-143: 424: 45.66
+	Dm
		853771 ISWI_DROME (683-1743): 0: 835: 24.51		IMA_DROME (3-538): 6.8e-121: 367: 43.41