Interactor 1: SRPK2 (P78362)
SRSF protein kinase 2 (EC 2.7.11.1) (SFRS protein kinase 2) (Serine/arginine-rich protein-specific kinase 2) (SR-protein-specific kinase 2) [Cleaved into: SRSF protein kinase 2 N-terminal; SRSF protein kinase 2 C-terminal]
Gene: SRPK2
Interactor 2: U2AF1 (Q01081)
Splicing factor U2AF 35 kDa subunit (U2 auxiliary factor 35 kDa subunit) (U2 small nuclear RNA auxiliary factor 1) (U2 snRNP auxiliary factor small subunit)
Gene: U2AF1
Species: Homo sapiens
Source: mint
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.92 | 1.00 | 0.963 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 28514442, 33961781, 22365833, 25416956, 34133714, 23602568 |
| Identification Methods | affinity chromatography technology, two hybrid, fluorescent resonance energy transfer, two hybrid prey pooling approach, two hybrid array, validated two hybrid, tandem affinity purification, anti tag coimmunoprecipitation, bimolecular fluorescence complementation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Pkinase~RRM_1 |
| Common GO terms | GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0008380 - RNA splicing GO:0016607 - nuclear speck |
| Homologous interactions | 8 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
