HitPredict

Interactor 1: TCPB (P78371)
T-complex protein 1 subunit beta (TCP-1-beta) (EC 3.6.1.-) (CCT-beta) (Chaperonin containing T-complex polypeptide 1 subunit 2)
Gene: CCT2

Interactor 2: WRP73 (Q9P2S5)
WD repeat-containing protein WRAP73 (WD repeat-containing protein 8) (WD repeat-containing protein antisense to TP73 gene)
Gene: WRAP73

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	26186194
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Cpn60_TCP1~WD40
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 535 Hs			1 460
+	Hs
		1007196 TCPB_HUMAN (1-535): 0: 586: 100.00		SNR40_HUMAN (170-459): 3.87e-59: 199: 11.07
+	Hs
		965190 TCPH_HUMAN (4-532): 0: 591: 34.08		WDR5_HUMAN (270-456): 9.39e-45: 161: 16.04
+	Hs
		964840 TCPB_HUMAN (1-535): 0: 586: 100.00		WDR5_HUMAN (270-456): 9.39e-45: 161: 16.04
+	Hs
		1291941 TCPH_HUMAN (4-532): 0: 591: 34.08		WDR5B_HUMAN (270-456): 2.26e-41: 151: 15.51
+	Hs
		1007118 TCPB_HUMAN (1-535): 0: 586: 100.00		WDR5B_HUMAN (270-456): 2.26e-41: 151: 15.51
+	Zm
		35499 G2XK63_MAIZE (11-530): 0: 565: 68.65		A0A1D6LKZ7_MAIZE (82-399): 4.31e-43: 164: 10.00
+	Hs
		881861 TCPG_HUMAN (3-532): 0: 561: 28.33		WDR5_HUMAN (270-456): 9.39e-45: 161: 16.04
+	Hs
		882014 TCPG_HUMAN (3-532): 0: 561: 28.33		WDR5B_HUMAN (270-456): 2.26e-41: 151: 15.51
+	Hs
		209325 TCPH_HUMAN (4-532): 0: 591: 34.08		PRP4_HUMAN (50-360): 9.09e-22: 99: 13.75
+	Hs
		845257 TCPG_HUMAN (3-532): 0: 561: 28.33		LIS1_HUMAN (2-166): 1.62e-32: 129: 13.37
+	Hs
		209247 TCPB_HUMAN (1-535): 0: 586: 100.00		PRP4_HUMAN (50-360): 9.09e-22: 99: 13.75
+	Hs
		1407594 TCPH_HUMAN (4-532): 0: 591: 34.08		NLE1_HUMAN (1-76): 3.65e-15: 79.4: 17.95
+	Hs
		1007162 TCPB_HUMAN (1-535): 0: 586: 100.00		POC1B_HUMAN (1-86): 4.02e-15: 79.4: 18.18
+	Hs
		1007305 TCPB_HUMAN (1-535): 0: 586: 100.00		NLE1_HUMAN (1-76): 3.65e-15: 79.4: 17.95
+	Hs
		1407542 TCPH_HUMAN (4-532): 0: 591: 34.08		KTNB1_HUMAN (8-171): 3.14e-13: 73.7: 18.08
+	Hs
		209218 TCPG_HUMAN (3-532): 0: 561: 28.33		PRP4_HUMAN (50-360): 9.09e-22: 99: 13.75
+	Hs
		1007244 TCPB_HUMAN (1-535): 0: 586: 100.00		KTNB1_HUMAN (8-171): 3.14e-13: 73.7: 18.08
+	Hs
		1334162 TCPH_HUMAN (4-532): 0: 591: 34.08		POC1A_HUMAN (1-76): 7.93e-12: 68.6: 15.39
+	Hs
		1007146 TCPB_HUMAN (1-535): 0: 586: 100.00		POC1A_HUMAN (1-76): 7.93e-12: 68.6: 15.39
+	Sc
		793919 TCPB_YEAST (9-532): 0: 566: 65.71		TAF5_YEAST (171-361): 1.61e-11: 68.7: 18.62