HitPredict

Interactor 1: ATL3 (P82987)
ADAMTS-like protein 3 (ADAMTSL-3) (Punctin-2)
Gene: ADAMTSL3

Interactor 2: NT2NA (Q7Z3S9)
Notch homolog 2 N-terminal-like protein A (Notch homolog 2 N-terminal-like protein)
Gene: NOTCH2NLA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.573

Property	Details
Experiments	25416956
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1691 Hs			1 236
+	Hs
		1013197 ATL3_HUMAN (1-1691): 0: 959: 100.00		NOTC2_HUMAN (8-180): 6.98e-16: 78.5: 27.84
+	Hs
		1251875 ATL5_HUMAN (75-341): 5.77e-74: 257: 29.35		NT2NA_HUMAN (1-236): 2.32e-45: 153: 100.00
+	Hs
		857435 CNTN1_HUMAN (1105-1526): 7.16e-46: 183: 15.37		NOTC1_HUMAN (68-233): 8.99e-17: 81.2: 27.84
+	Hs
		1047529 CNTN1_HUMAN (1105-1526): 7.16e-46: 183: 15.37		NOTC2_HUMAN (8-180): 6.98e-16: 78.5: 27.84
+	Hs
		1250247 ATL4_HUMAN (82-421): 2.56e-09: 64.3: 12.47		NT2NA_HUMAN (1-236): 2.32e-45: 153: 100.00
+	Ce
		109601 SAX3_CAEEL (892-1203): 2.45e-19: 97.5: 7.90		SLIT1_CAEEL (86-233): 2.77e-21: 93.9: 27.74
+	Mm
		313303 ROBO1_MOUSE (1291-1531): 1.34e-23: 111: 15.23		SLIT3_MOUSE (71-185): 1.69e-11: 65.4: 26.89
+	Hs
		317597 ROBO1_HUMAN (1289-1531): 1.91e-24: 114: 15.50		SLIT2_HUMAN (67-185): 9.77e-10: 60: 30.89
+	Hs
		1047765 ATS9_HUMAN (1428-1650): 1.22e-18: 95.2: 21.70		NOTC2_HUMAN (8-180): 6.98e-16: 78.5: 27.84
+	Hs
		1047656 ATS17_HUMAN (448-934): 2.22e-16: 87.5: 14.81		NOTC2_HUMAN (8-180): 6.98e-16: 78.5: 27.84
+	Dm
		753703 Q0E8N3_DROME (1548-1690): 1.66e-09: 65.1: 16.97		FAT_DROME (146-236): 6.03e-21: 93.2: 24.37
+	Hs
		1047773 ATS1_HUMAN (1601-1691): 3.28e-10: 67.4: 21.98		NOTC2_HUMAN (8-180): 6.98e-16: 78.5: 27.84
+	Hs
		1047657 ATS15_HUMAN (501-783): 4.5e-10: 67: 14.48		NOTC2_HUMAN (8-180): 6.98e-16: 78.5: 27.84
+	Hs
		946232 ATS12_HUMAN (757-886): 3.18e-09: 64.3: 22.90		NOTC2_HUMAN (8-180): 6.98e-16: 78.5: 27.84
+	Hs
		517045 ATL4_HUMAN (82-421): 2.56e-09: 64.3: 12.47		NT2NC_HUMAN (69-233): 1.56e-13: 70.1: 32.37
+	Hs
		1250351 ATS13_HUMAN (1367-1551): 1.09e-09: 65.9: 24.60		FAT4_HUMAN (65-173): 1.1e-11: 66.2: 27.03
+	Hs
		270507 ATL4_HUMAN (82-421): 2.56e-09: 64.3: 12.47		SLIT1_HUMAN (68-230): 2.62e-09: 58.9: 19.76