Interactor 1: AP2M1 (P84091)
AP-2 complex subunit mu (AP-2 mu chain) (Adaptor protein complex AP-2 subunit mu) (Adaptor-related protein complex 2 subunit mu) (Clathrin assembly protein complex 2 mu medium chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (Mu2-adaptin) (Plasma membrane adaptor AP-2 50 kDa protein)
Gene: AP2M1

Interactor 2: AP2M1 (P84091)
AP-2 complex subunit mu (AP-2 mu chain) (Adaptor protein complex AP-2 subunit mu) (Adaptor-related protein complex 2 subunit mu) (Clathrin assembly protein complex 2 mu medium chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (Mu2-adaptin) (Plasma membrane adaptor AP-2 50 kDa protein)
Gene: AP2M1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 29199018
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Adap_comp_sub~Adap_comp_sub, Adap_comp_sub~Clat_adaptor_s, Clat_adaptor_s~Clat_adaptor_s
Common GO terms GO:0002092 - positive regulation of receptor internalization
GO:0005048 - signal sequence binding
GO:0005739 - mitochondrion
GO:0006886 - intracellular protein transport
GO:0006900 - vesicle budding from membrane
and 20 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 435
Mm

1 435
+ Hs
+ Hs
+ Dm
+ At
+ Sc
+ Sc
+ Hs
+ Hs
+ Rn
+ Sc
+ Sc

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Last updated: 11Aug2025