HitPredict

Interactor 1: SNF5 (Q12824)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 (BRG1-associated factor 47) (BAF47) (Integrase interactor 1 protein) (SNF5 homolog) (hSNF5)
Gene: SMARCB1

Interactor 2: KMT2C (Q8NEZ4)
Histone-lysine N-methyltransferase 2C (Lysine N-methyltransferase 2C) (EC 2.1.1.364) (Homologous to ALR protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 3)
Gene: KMT2C

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.46	0.60	0.527

Property	Details
Experiments	19221051
Identification Methods	pull down, two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0003713 - transcription coactivator activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 385 Hs			1 4911
+	Hs
		1017136 SNF5_HUMAN (1-385): 0: 658: 100.00		EZH2_HUMAN (4563-4893): 4.31e-83: 294: 20.99
+	Hs
		975234 SNF5_HUMAN (1-385): 0: 658: 100.00		KMT2A_HUMAN (159-332): 7.57e-32: 140: 22.16
+	Hs
		1017103 SNF5_HUMAN (1-385): 0: 658: 100.00		CHD3_HUMAN (390-526): 1.86e-31: 139: 21.38
+	Hs
		1017192 SNF5_HUMAN (1-385): 0: 658: 100.00		DPF1_HUMAN (350-435): 3.04e-13: 77: 40.45
+	Hs
		1017194 SNF5_HUMAN (1-385): 0: 658: 100.00		REQU_HUMAN (359-435): 2.72e-12: 74.3: 41.25
+	Hs
		1017193 SNF5_HUMAN (1-385): 0: 658: 100.00		DPF3_HUMAN (359-435): 1.11e-11: 72: 40.00
+	Hs
		1017260 SNF5_HUMAN (1-385): 0: 658: 100.00		KMT2B_HUMAN (1985-2617): 4.3e-09: 65.8: 12.11
+	Dm
		594801 Q24090_DROME (4-385): 0: 564: 65.54		TRX_DROME (36-334): 3.76e-23: 112: 18.38
+	Dm
		1095772 Q24090_DROME (4-385): 0: 564: 65.54		Q7K3G5_DROME (359-435): 1.38e-13: 79: 42.50