HitPredict

Interactor 1: BPTF (Q12830)
Nucleosome-remodeling factor subunit BPTF (Bromodomain and PHD finger-containing transcription factor) (Fetal Alz-50 clone 1 protein) (Fetal Alzheimer antigen)
Gene: BPTF

Interactor 2: SIN3A (Q96ST3)
Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a)
Gene: SIN3A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 3046 Hs			1 1273
+	Hs
		1018652 CHD3_HUMAN (356-439): 2.17e-18: 95.6: 33.33		SIN3A_HUMAN (1-1273): 0: 1545: 100.00
+	Hs
		244825 BRD4_HUMAN (2936-3028): 1.03e-10: 70.1: 41.05		SIN3A_HUMAN (1-1273): 0: 1545: 100.00
+	Hs
		1300903 CIC_HUMAN (1024-2323): 3.62e-09: 65.2: 8.69		SIN3A_HUMAN (1-1273): 0: 1545: 100.00
+	Hs
		257773 BPTF_HUMAN (1-3046): 0: 1372: 100.00		SIN3B_HUMAN (20-331): 1.12e-13: 78.4: 16.15
+	Sc
		609137 GCN5_YEAST (2887-3033): 4.12e-45: 173: 32.65		SIN3_YEAST (20-499): 1.06e-32: 140: 14.02
+	Hs
		257851 ZMYD8_HUMAN (2811-3032): 9.21e-40: 165: 24.61		SIN3B_HUMAN (20-331): 1.12e-13: 78.4: 16.15
+	Hs
		257774 CHD3_HUMAN (356-439): 2.17e-18: 95.6: 33.33		SIN3B_HUMAN (20-331): 1.12e-13: 78.4: 16.15
+	Hs
		257822 CIC_HUMAN (1024-2323): 3.62e-09: 65.2: 8.69		SIN3B_HUMAN (20-331): 1.12e-13: 78.4: 16.15