HitPredict

Interactor 1: H33 (P84244)
Histone H3.3
Gene: H3-3a

Interactor 2: ATRX (Q61687)
Transcriptional regulator ATRX (EC 3.6.4.12) (ATP-dependent helicase ATRX) (HP1 alpha-interacting protein) (HP1-BP38 protein) (Heterochromatin protein 2) (X-linked nuclear protein)
Gene: ATRX

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	20211137
Identification Methods	pull down, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~SNF2-rel_dom
Common GO terms	GO:0000781 - chromosome, telomeric region GO:0005634 - nucleus GO:0006334 - nucleosome assembly GO:0007283 - spermatogenesis GO:0031509 - subtelomeric heterochromatin formation and 1 others more... GO:0035264 - multicellular organism growth
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Mm			1 2476
+	Hs
		855423 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		ATRX_HUMAN (1-2476): 0: 960: 81.27
+	Hs
		855427 H33_HUMAN (1-136): 1.13e-59: 182: 100.00		ATRX_HUMAN (1-2476): 0: 960: 81.27
+	Hs
		998851 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		HELLS_HUMAN (1367-2228): 3.66e-148: 486: 19.03
+	Hs
		998804 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		SMRCD_HUMAN (1051-2192): 1.11e-133: 450: 17.64
+	Hs
		998313 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		HLTF_HUMAN (1320-2193): 8.72e-125: 423: 16.74
+	Hs
		998577 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		CHD5_HUMAN (1873-2445): 6.73e-89: 326: 18.41
+	Mm
		59101 H33_MOUSE (1-136): 1.13e-59: 182: 100.00		CHD5_MOUSE (1873-2445): 3.38e-85: 314: 18.41
+	Hs
		998258 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		CHD3_HUMAN (1873-2445): 7.9e-82: 303: 19.90
+	Hs
		998324 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		CHD4_HUMAN (1873-2445): 7.16e-76: 283: 19.16
+	Hs
		903310 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		SMCA4_HUMAN (1995-2258): 1.91e-68: 259: 25.50
+	Hs
		903314 H33_HUMAN (1-136): 1.13e-59: 182: 100.00		SMCA4_HUMAN (1995-2258): 1.91e-68: 259: 25.50
+	Hs
		999008 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		RA54B_HUMAN (2066-2199): 7.85e-24: 112: 41.26
+	Hs
		998236 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		ERCC6_HUMAN (1544-1837): 3.9e-17: 90.9: 27.36
+	Hs
		1016792 H33_HUMAN (1-136): 1.13e-59: 182: 100.00		ERCC6_HUMAN (1544-1837): 3.9e-17: 90.9: 27.36
+	Mm
		999034 H31_MOUSE (1-136): 3.09e-60: 183: 96.32		SMCA5_MOUSE (1572-1872): 5.19e-14: 80.5: 28.29
+	Hs
		703289 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		SMCA1_HUMAN (1572-1872): 9.82e-14: 79.7: 28.29
+	Mm
		1017370 H33_MOUSE (1-136): 1.13e-59: 182: 100.00		SMCA5_MOUSE (1572-1872): 5.19e-14: 80.5: 28.29
+	Hs
		243594 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		SMCA5_HUMAN (1572-1872): 1.17e-13: 79.3: 27.96
+	Hs
		703293 H33_HUMAN (1-136): 1.13e-59: 182: 100.00		SMCA1_HUMAN (1572-1872): 9.82e-14: 79.7: 28.29
+	Hs
		243599 H33_HUMAN (1-136): 1.13e-59: 182: 100.00		SMCA5_HUMAN (1572-1872): 1.17e-13: 79.3: 27.96