HitPredict

Interactor 1: H33 (P84244)
Histone H3.3
Gene: H3-3a

Interactor 2: Q9JM08 (Q9JM08)
Histone deacetylase (EC 3.5.1.98)
Gene: Hdac3

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24115035
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Hist_deacetyl~Histone
Common GO terms	GO:0005634 - nucleus
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 136 Mm			1 428
+	Hs
		188235 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		HDAC3_HUMAN (1-428): 0: 606: 99.07
+	Hs
		998289 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		HDAC1_HUMAN (3-385): 0: 587: 62.66
+	Hs
		1016836 H33_HUMAN (1-136): 1.13e-59: 182: 100.00		HDAC1_HUMAN (3-385): 0: 587: 62.66
+	Hs
		1109771 H31T_HUMAN (1-136): 2.59e-59: 181: 93.38		HDAC1_HUMAN (3-385): 0: 587: 62.66
+	Hs
		117244 K7EK07_HUMAN (1-132): 7.85e-58: 177: 100.00		HDAC1_HUMAN (3-385): 0: 587: 62.66
+	Hs
		998626 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		HDAC2_HUMAN (3-422): 0: 578: 58.39
+	Hs
		1017073 H33_HUMAN (1-136): 1.13e-59: 182: 100.00		HDAC2_HUMAN (3-422): 0: 578: 58.39
+	Hs
		1161972 H31T_HUMAN (1-136): 2.59e-59: 181: 93.38		HDAC2_HUMAN (3-422): 0: 578: 58.39
+	Hs
		883531 CENPA_HUMAN (9-133): 2.43e-45: 146: 50.76		HDAC1_HUMAN (3-385): 0: 587: 62.66
+	Sc
		739901 H3_YEAST (1-136): 3.63e-54: 168: 90.44		RPD3_YEAST (3-414): 0: 541: 56.60
+	At
		947416 H33_ARATH (1-136): 3.85e-60: 183: 95.59		HDA6_ARATH (3-423): 0: 522: 55.32
+	Ce
		196411 HCP3_CAEEL (11-131): 4.33e-45: 149: 49.19		HDA1_CAEEL (3-427): 0: 550: 53.69
+	Sp
		149005 H31_SCHPO (1-136): 1.12e-57: 177: 91.91		PHD1_SCHPO (3-409): 0: 521: 55.39
+	Sc
		917106 H3_YEAST (1-136): 3.63e-54: 168: 90.44		HOS2_YEAST (4-420): 5.15e-175: 498: 49.88
+	Hs
		998767 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		HDAC8_HUMAN (26-367): 1.29e-136: 398: 42.69
+	Hs
		1162030 H31T_HUMAN (1-136): 2.59e-59: 181: 93.38		HDAC8_HUMAN (26-367): 1.29e-136: 398: 42.69
+	Sc
		925462 H3_YEAST (1-136): 3.63e-54: 168: 90.44		HDA1_YEAST (4-351): 1.44e-113: 350: 21.29