HitPredict

Interactor 1: H31T (Q16695)
Histone H3.1t (H3/t) (H3t) (H3/g) (Histone H3.4)
Gene: H3-4

Interactor 2: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	12700765
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Hist_deacetyl~Histone
Common GO terms	GO:0000781 - chromosome, telomeric region GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 136 Hs			1 488
+	Hs
		998626 H31_HUMAN (1-136): 3.36e-62: 188: 97.06		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		1017073 H33_HUMAN (1-136): 1.86e-61: 186: 93.38		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		998289 H31_HUMAN (1-136): 3.36e-62: 188: 97.06		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		1109771 H31T_HUMAN (1-136): 1.34e-61: 187: 100.00		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		1016836 H33_HUMAN (1-136): 1.86e-61: 186: 93.38		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		117244 K7EK07_HUMAN (1-132): 1.4e-59: 181: 93.18		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		883531 CENPA_HUMAN (9-133): 3.55e-44: 142: 49.24		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	At
		947416 H33_ARATH (1-136): 6.71e-62: 187: 93.38		HDA6_ARATH (1-467): 0: 578: 57.02
+	Hs
		188235 H31_HUMAN (1-136): 3.36e-62: 188: 97.06		HDAC3_HUMAN (10-431): 0: 574: 58.26
+	Mm
		1017380 H33_MOUSE (1-136): 1.86e-61: 186: 93.38		Q9JM08_MOUSE (10-431): 0: 568: 58.02
+	Sc
		739901 H3_YEAST (1-136): 8.07e-56: 172: 86.03		RPD3_YEAST (5-422): 0: 577: 60.95
+	Ce
		196411 HCP3_CAEEL (11-131): 1.35e-44: 148: 46.77		HDA1_CAEEL (7-456): 0: 595: 64.02
+	Sp
		149005 H31_SCHPO (1-136): 2.84e-59: 181: 88.97		PHD1_SCHPO (7-411): 0: 519: 52.56
+	Sc
		917106 H3_YEAST (1-136): 8.07e-56: 172: 86.03		HOS2_YEAST (11-430): 5.05e-174: 498: 47.18
+	Hs
		998767 H31_HUMAN (1-136): 3.36e-62: 188: 97.06		HDAC8_HUMAN (33-372): 1.02e-137: 403: 43.40
+	Hs
		1162030 H31T_HUMAN (1-136): 1.34e-61: 187: 100.00		HDAC8_HUMAN (33-372): 1.02e-137: 403: 43.40
+	Sc
		925462 H3_YEAST (1-136): 8.07e-56: 172: 86.03		HDA1_YEAST (9-330): 1.24e-121: 373: 27.56
+	Hs
		998904 H31_HUMAN (1-136): 3.36e-62: 188: 97.06		HDAC6_HUMAN (11-363): 6.97e-102: 332: 24.04