HitPredict

Interactor 1: P91857 (P91857)
small monomeric GTPase (EC 3.6.5.2)
Gene: rab-5

Interactor 2: REP1 (Q9BKQ5)
Rab proteins geranylgeranyltransferase component A 1 (Rab escort protein 1) (TCD protein)
Gene: rep-1

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	19090809
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	GDI~Ras
Common GO terms	GO:0006886 - intracellular protein transport
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 208 Ce			1 510
+	Hs
		724459 RAB5B_HUMAN (1-207): 2.28e-99: 288: 75.35		GDIA_HUMAN (5-496): 0: 578: 22.31
+	Hs
		894523 RAB5B_HUMAN (1-207): 2.28e-99: 288: 75.35		GDIB_HUMAN (5-496): 0: 574: 21.91
+	Mm
		894618 RAB1A_MOUSE (9-207): 7.12e-89: 261: 41.95		GDIA_MOUSE (5-496): 0: 581: 22.31
+	Hs
		724464 RAB1A_HUMAN (9-207): 7.12e-89: 261: 41.95		GDIA_HUMAN (5-496): 0: 578: 22.31
+	Dm
		1463771 RAB5_DROME (2-208): 1.88e-95: 278: 71.09		Q9VLB7_DROME (5-501): 0: 559: 22.84
+	Hs
		724449 RAB5C_HUMAN (1-207): 3.45e-87: 257: 72.90		GDIA_HUMAN (5-496): 0: 578: 22.31
+	Hs
		894530 RAB1A_HUMAN (9-207): 7.12e-89: 261: 41.95		GDIB_HUMAN (5-496): 0: 574: 21.91
+	Hs
		724515 RAB1B_HUMAN (12-207): 4.9e-87: 256: 41.29		GDIA_HUMAN (5-496): 0: 578: 22.31
+	Hs
		894508 RAB5C_HUMAN (1-207): 3.45e-87: 257: 72.90		GDIB_HUMAN (5-496): 0: 574: 21.91
+	Hs
		894591 RAB1B_HUMAN (12-207): 4.9e-87: 256: 41.29		GDIB_HUMAN (5-496): 0: 574: 21.91
+	Dm
		197101 O18332_DROME (9-207): 1.08e-86: 256: 40.49		Q9VLB7_DROME (5-501): 0: 559: 22.84
+	Hs
		664856 RAB5B_HUMAN (1-207): 2.28e-99: 288: 75.35		RAE1_HUMAN (1-73): 1.56e-24: 109: 43.84
+	Hs
		686572 RAB1A_HUMAN (9-207): 7.12e-89: 261: 41.95		RAE2_HUMAN (1-99): 2.19e-25: 112: 39.39
+	Hs
		664861 RAB1A_HUMAN (9-207): 7.12e-89: 261: 41.95		RAE1_HUMAN (1-73): 1.56e-24: 109: 43.84
+	Hs
		686559 RAB5C_HUMAN (1-207): 3.45e-87: 257: 72.90		RAE2_HUMAN (1-99): 2.19e-25: 112: 39.39
+	Hs
		686592 RAB1B_HUMAN (12-207): 4.9e-87: 256: 41.29		RAE2_HUMAN (1-99): 2.19e-25: 112: 39.39
+	Hs
		664849 RAB5C_HUMAN (1-207): 3.45e-87: 257: 72.90		RAE1_HUMAN (1-73): 1.56e-24: 109: 43.84
+	Hs
		664903 RAB1B_HUMAN (12-207): 4.9e-87: 256: 41.29		RAE1_HUMAN (1-73): 1.56e-24: 109: 43.84
+	Hs
		686579 RB11B_HUMAN (9-208): 7.33e-83: 247: 38.43		RAE2_HUMAN (1-99): 2.19e-25: 112: 39.39
+	Hs
		664874 RB11B_HUMAN (9-208): 7.33e-83: 247: 38.43		RAE1_HUMAN (1-73): 1.56e-24: 109: 43.84