HitPredict

Interactor 1: RAB5 (Q9V3I2)
Ras-related protein Rab5 (Drab5) (EC 3.6.5.2) (Small monomeric GTPase Rab5)
Gene: RAB5

Interactor 2: Q9VLB7 (Q9VLB7)
Rab GDP dissociation inhibitor
Gene: Gdi

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	25453831, 25242320
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	GDI~Ras
Common GO terms	GO:0005829 - cytosol GO:0008021 - synaptic vesicle GO:0016192 - vesicle-mediated transport
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 219 Dm			1 443
+	Hs
		724459 RAB5B_HUMAN (12-218): 1.49e-100: 291: 72.17		GDIA_HUMAN (1-440): 0: 678: 67.80
+	Hs
		894523 RAB5B_HUMAN (12-218): 1.49e-100: 291: 72.17		GDIB_HUMAN (1-440): 0: 670: 67.80
+	Dm
		197373 O18335_DROME (19-219): 1.78e-86: 256: 39.25		Q9VLB7_DROME (1-443): 0: 692: 100.00
+	Mm
		894618 RAB1A_MOUSE (19-218): 9.07e-89: 261: 38.05		GDIA_MOUSE (1-440): 0: 680: 68.03
+	Hs
		724464 RAB1A_HUMAN (19-218): 9.07e-89: 261: 38.05		GDIA_HUMAN (1-440): 0: 678: 67.80
+	Hs
		724515 RAB1B_HUMAN (22-218): 2.69e-87: 257: 39.30		GDIA_HUMAN (1-440): 0: 678: 67.80
+	Hs
		631084 RAB5A_HUMAN (10-218): 1.46e-86: 256: 70.89		GDIA_HUMAN (1-440): 0: 678: 67.80
+	Hs
		894530 RAB1A_HUMAN (19-218): 9.07e-89: 261: 38.05		GDIB_HUMAN (1-440): 0: 670: 67.80
+	Hs
		894591 RAB1B_HUMAN (22-218): 2.69e-87: 257: 39.30		GDIB_HUMAN (1-440): 0: 670: 67.80
+	Hs
		631123 RAB5A_HUMAN (10-218): 1.46e-86: 256: 70.89		GDIB_HUMAN (1-440): 0: 670: 67.80
+	Ce
		1019446 P91857_CAEEL (9-219): 1.74e-99: 288: 71.09		REP1_CAEEL (3-431): 7.12e-141: 414: 24.39
+	Dm
		197353 O18335_DROME (19-219): 1.78e-86: 256: 39.25		RABEP_DROME (3-424): 2.51e-131: 390: 23.54
+	Hs
		664856 RAB5B_HUMAN (12-218): 1.49e-100: 291: 72.17		RAE1_HUMAN (4-47): 1.13e-12: 71.9: 52.27
+	Hs
		686572 RAB1A_HUMAN (19-218): 9.07e-89: 261: 38.05		RAE2_HUMAN (4-67): 2.77e-13: 73.9: 39.06
+	Hs
		664861 RAB1A_HUMAN (19-218): 9.07e-89: 261: 38.05		RAE1_HUMAN (4-47): 1.13e-12: 71.9: 52.27
+	Hs
		686592 RAB1B_HUMAN (22-218): 2.69e-87: 257: 39.30		RAE2_HUMAN (4-67): 2.77e-13: 73.9: 39.06
+	Hs
		631066 RAB5A_HUMAN (10-218): 1.46e-86: 256: 70.89		RAE2_HUMAN (4-67): 2.77e-13: 73.9: 39.06
+	Hs
		664903 RAB1B_HUMAN (22-218): 2.69e-87: 257: 39.30		RAE1_HUMAN (4-47): 1.13e-12: 71.9: 52.27
+	Hs
		631063 RAB5A_HUMAN (10-218): 1.46e-86: 256: 70.89		RAE1_HUMAN (4-47): 1.13e-12: 71.9: 52.27
+	Hs
		664849 RAB5C_HUMAN (10-218): 1.71e-86: 256: 73.36		RAE1_HUMAN (4-47): 1.13e-12: 71.9: 52.27