Protein: THIO2
Thioredoxin 2 (Trx-2) (EC 1.8.1.8) (Protein-disulfide reductase)

Gene: THIO2, trxC
Organism: Escherichia coli K-12
Interactions: 26
UniProt ID: P0AGG4

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0008270 - zinc ion binding
GO:0015035 - protein-disulfide reductase activity
GO:0047134 - protein-disulfide reductase [NAD(P)H] activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

497017

DLDH
Dihydrolipoyl dehydrogenase

1

11

High-throughput

0.691

High

473289

DNAJ
Chaperone protein DnaJ

1

0

High-throughput

0.593

High

498919

PHSG
Glycogen phosphorylase

2

1

High-throughput

0.588

High

501570

CODA
Cytosine deaminase

2

0

High-throughput

0.563

High

501572

PT1P
Phosphoenolpyruvate-dependent phosphotransferase system

1

1

High-throughput

0.541

High

500181

MGLB
D-galactose/methyl-galactoside binding periplasmic protein MglB

2

2

High-throughput

0.537

High

500532

MDFA
Multidrug transporter MdfA

2

3

High-throughput

0.537

High

449851

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex

1

4

High-throughput

0.536

High

494103

RS4
Small ribosomal subunit protein uS4

1

1

High-throughput

0.536

High

496790

SLYD
FKBP-type peptidyl-prolyl cis-trans isomerase SlyD

1

1

High-throughput

0.536

High

491635

KPRS
Ribose-phosphate pyrophosphokinase

1

0

High-throughput

0.513

High

500784

ODP1
Pyruvate dehydrogenase E1 component

1

0

High-throughput

0.513

High

501567

MURD
UDP-N-acetylmuramoylalanine--D-glutamate ligase

1

0

High-throughput

0.513

High

501568

PARE
DNA topoisomerase 4 subunit B

1

0

High-throughput

0.513

High

501576

RL2
Large ribosomal subunit protein uL2

1

0

High-throughput

0.513

High

501577

RL4
Large ribosomal subunit protein uL4

1

0

High-throughput

0.513

High

501581

THII
tRNA sulfurtransferase

1

0

High-throughput

0.513

High

491108

DNAK
Chaperone protein DnaK

1

17

High-throughput

0.484

High

501571

YDBA
Exported protein YdbA

1

1

High-throughput

0.407

High

501578

REQ2
Prophage antitermination protein Q homolog QuuQ

1

0

High-throughput

0.282

High

501569

HIPB
Antitoxin HipB

1

0

High-throughput

0.279

Low

501573

KILR
Killing protein KilR

1

0

High-throughput

0.279

Low

501574

YHBQ
UPF0213 protein YhbQ

1

0

High-throughput

0.279

Low

501575

HOFO
DNA utilization protein HofO

1

0

High-throughput

0.279

Low

501579

YBDM
Uncharacterized protein YbdM

1

0

High-throughput

0.279

Low

501580

ECPB
Probable fimbrial chaperone EcpB

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025