Interactor 1: PKD1 (P98161)
Polycystin-1 (PC1) (Autosomal dominant polycystic kidney disease 1 protein)
Gene: PKD1
Interactor 2: PTPRS (Q13332)
Receptor-type tyrosine-protein phosphatase S (R-PTP-S) (EC 3.1.3.48) (Receptor-type tyrosine-protein phosphatase sigma) (R-PTP-sigma)
Gene: PTPRS
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 21126580 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Lectin_C~fn3, I-set~LRR_8, Ig_3~LRR_8 |
| Common GO terms | GO:0005886 - plasma membrane GO:0021510 - spinal cord development GO:0070062 - extracellular exosome |
| Homologous interactions | 4 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
