HitPredict

Interactor 1: TFAM (Q00059)
Transcription factor A, mitochondrial (mtTFA) (Mitochondrial transcription factor 1) (MtTF1) (Transcription factor 6) (TCF-6) (Transcription factor 6-like 2)
Gene: TFAM

Interactor 2: BRD3 (Q15059)
Bromodomain-containing protein 3 (RING3-like protein)
Gene: BRD3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30554943
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 726
+	Hs
		1141322 HM20A_HUMAN (45-146): 9.12e-25: 102: 19.61		BRD3_HUMAN (1-702): 1.03e-155: 470: 100.00
+	Hs
		186651 HMGB3_HUMAN (46-136): 4.08e-18: 81.4: 21.98		BRD3_HUMAN (1-702): 1.03e-155: 470: 100.00
+	Hs
		259798 TFAM_HUMAN (1-246): 2.64e-63: 199: 100.00		BRD4_HUMAN (3-644): 3.51e-104: 349: 52.55
+	Hs
		260487 HM20A_HUMAN (45-146): 9.12e-25: 102: 19.61		BRD4_HUMAN (3-644): 3.51e-104: 349: 52.55
+	Hs
		186601 HMGB3_HUMAN (46-136): 4.08e-18: 81.4: 21.98		BRD4_HUMAN (3-644): 3.51e-104: 349: 52.55
+	Hs
		259605 SOX9_HUMAN (140-241): 6.32e-16: 78.3: 15.09		BRD4_HUMAN (3-644): 3.51e-104: 349: 52.55
+	Hs
		1024232 TFAM_HUMAN (1-246): 2.64e-63: 199: 100.00		ZMYD8_HUMAN (3-713): 1.39e-58: 217: 12.28
+	Hs
		1024229 TFAM_HUMAN (1-246): 2.64e-63: 199: 100.00		BRPF3_HUMAN (20-316): 1.15e-29: 128: 14.29
+	Hs
		1445911 HM20A_HUMAN (45-146): 9.12e-25: 102: 19.61		ZMYD8_HUMAN (3-713): 1.39e-58: 217: 12.28
+	Hs
		1067662 SOX7_HUMAN (121-230): 9.38e-20: 89.1: 14.91		EP300_HUMAN (4-177): 1.06e-35: 148: 23.43
+	Hs
		942093 SOX10_HUMAN (140-242): 5.12e-17: 81.4: 15.32		EP300_HUMAN (4-177): 1.06e-35: 148: 23.43
+	Hs
		239945 SOX15_HUMAN (115-231): 3.67e-17: 79.4: 14.88		EP300_HUMAN (4-177): 1.06e-35: 148: 23.43
+	Hs
		873076 SOX9_HUMAN (140-241): 6.32e-16: 78.3: 15.09		EP300_HUMAN (4-177): 1.06e-35: 148: 23.43
+	Rn
		98827 SOX9_RAT (140-241): 4.48e-16: 78.7: 15.09		F1M9G7_RAT (27-177): 7.45e-34: 142: 26.32
+	Hs
		1413224 SOX7_HUMAN (121-230): 9.38e-20: 89.1: 14.91		CECR2_HUMAN (130-557): 3.68e-29: 126: 14.78
+	Hs
		1287980 SOX7_HUMAN (121-230): 9.38e-20: 89.1: 14.91		PB1_HUMAN (152-486): 2.23e-20: 99.1: 12.85
+	Hs
		1287989 SOX17_HUMAN (119-233): 5.01e-19: 87.1: 14.29		PB1_HUMAN (152-486): 2.23e-20: 99.1: 12.85
+	Hs
		942109 SOX10_HUMAN (140-242): 5.12e-17: 81.4: 15.32		PB1_HUMAN (152-486): 2.23e-20: 99.1: 12.85
+	Hs
		239966 SOX15_HUMAN (115-231): 3.67e-17: 79.4: 14.88		PB1_HUMAN (152-486): 2.23e-20: 99.1: 12.85
+	Hs
		873100 SOX9_HUMAN (140-241): 6.32e-16: 78.3: 15.09		PB1_HUMAN (152-486): 2.23e-20: 99.1: 12.85