Protein: SOX10
Transcription factor SOX-10

Gene: SOX10
Organism: Homo sapiens
Interactions: 76
UniProt ID: P56693

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

942089

PO6F2
POU domain, class 6, transcription factor 2

2

20

High-throughput

0.783

High

764590

CTNB1
Catenin beta-1

1

20

Small-scale

0.724

High

629509

PO3F2
POU domain, class 3, transcription factor 2

1

20

Small-scale

0.713

High

942083

SOX10
Transcription factor SOX-10

1

19

Small-scale

0.713

High

662313

PAX3
Paired box protein Pax-3

2

20

Small-scale

0.643

High

942088

UBC9
SUMO-conjugating enzyme UBC9

2

10

Small-scale

0.631

High

942090

TFAM
Transcription factor A, mitochondrial

1

20

High-throughput

0.618

High

942109

PB1
Protein polybromo-1

1

20

High-throughput

0.618

High

942121

CIC
Protein capicua homolog

1

19

High-throughput

0.618

High

942124

HM20A
High mobility group protein 20A

1

20

High-throughput

0.618

High

209976

CRX
Cone-rod homeobox protein

2

20

High-throughput

0.606

High

942099

DAZP2
DAZ-associated protein 2

2

1

High-throughput

0.606

High

942129

HSF4
Heat shock factor protein 4

2

1

High-throughput

0.606

High

942131

MAGD1
Melanoma-associated antigen D1

2

8

High-throughput

0.606

High

473891

NFIC
Nuclear factor 1 C-type

1

20

High-throughput

0.561

High

942091

CDK6
Cyclin-dependent kinase 6

1

13

Small-scale

0.550

High

942097

NMI
N-myc-interactor

1

0

Small-scale

0.549

High

540834

ERG
Transcriptional regulator ERG

1

20

High-throughput

0.541

High

923654

RCAN1
Calcipressin-1

1

1

High-throughput

0.541

High

942114

RSPH1
Radial spoke head 1 homolog

1

5

High-throughput

0.541

High

891410

GSK3B
Glycogen synthase kinase-3 beta

1

11

Small-scale

0.536

High

142920

NFIB
Nuclear factor 1 B-type

1

20

High-throughput

0.515

High

942094

NFIA
Nuclear factor 1 A-type

1

20

High-throughput

0.515

High

603218

KPCA
Protein kinase C alpha type

1

10

High-throughput

0.515

High

942085

1433G
14-3-3 protein gamma

1

19

High-throughput

0.515

High

942086

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

13

High-throughput

0.515

High

942100

SETB1
Histone-lysine N-methyltransferase SETDB1

1

20

High-throughput

0.515

High

942112

LMO3
LIM domain only protein 3

1

20

High-throughput

0.515

High

942117

KAT5
Histone acetyltransferase KAT5

1

8

High-throughput

0.515

High

703520

MK01
Mitogen-activated protein kinase 1

1

9

Small-scale

0.501

High

775817

HNF1B
Hepatocyte nuclear factor 1-beta

1

20

High-throughput

0.501

High

942098

NFIX
Nuclear factor 1 X-type

1

20

High-throughput

0.501

High

942095

TIAM1
Rho guanine nucleotide exchange factor TIAM1

1

2

High-throughput

0.494

High

138985

BCL9
B-cell CLL/lymphoma 9 protein

1

20

High-throughput

0.479

High

154659

ARI1A
AT-rich interactive domain-containing protein 1A

1

20

High-throughput

0.479

High

161440

KMT2D
Histone-lysine N-methyltransferase 2D

1

20

High-throughput

0.479

High

174332

ZN609
Zinc finger protein 609

1

20

High-throughput

0.479

High

194536

KDM6A
Lysine-specific demethylase 6A

1

19

High-throughput

0.479

High

261391

TBL1X
F-box-like/WD repeat-containing protein TBL1X

1

20

High-throughput

0.479

High

278288

NCOR1
Nuclear receptor corepressor 1

1

20

High-throughput

0.479

High

505539

ATX1L
Ataxin-1-like

1

14

High-throughput

0.479

High

587039

ITF2
Transcription factor 4

1

5

Small-scale

0.479

High

903112

SMCA2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2

1

20

High-throughput

0.479

High

916075

NKX25
Homeobox protein Nkx-2.5

1

20

High-throughput

0.479

High

942084

DCAF7
DDB1- and CUL4-associated factor 7

1

20

High-throughput

0.479

High

942092

TLE1
Transducin-like enhancer protein 1

1

20

High-throughput

0.479

High

942093

EP300
Histone acetyltransferase p300

1

20

High-throughput

0.479

High

942096

GPS2
G protein pathway suppressor 2

1

4

High-throughput

0.479

High

942101

NCOA2
Nuclear receptor coactivator 2

1

20

High-throughput

0.479

High

942102

ARI4B
AT-rich interactive domain-containing protein 4B

1

20

High-throughput

0.479

High

942103

BCL7A
B-cell CLL/lymphoma 7 protein family member A

1

11

High-throughput

0.479

High

942104

BRM1L
Breast cancer metastasis-suppressor 1-like protein

1

8

High-throughput

0.479

High

942106

ARID2
AT-rich interactive domain-containing protein 2

1

20

High-throughput

0.479

High

942107

PAXI1
PAX-interacting protein 1

1

20

High-throughput

0.479

High

942108

LDB1
LIM domain-binding protein 1

1

5

High-throughput

0.479

High

942111

ARI1B
AT-rich interactive domain-containing protein 1B

1

20

High-throughput

0.479

High

942113

PHF10
PHD finger protein 10

1

20

High-throughput

0.479

High

942115

DPF1
Zinc finger protein neuro-d4

1

20

High-throughput

0.479

High

942116

REQU
Zinc finger protein ubi-d4

1

20

High-throughput

0.479

High

942118

FBXW7
F-box/WD repeat-containing protein 7

1

19

Small-scale

0.479

High

942120

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

1

11

High-throughput

0.479

High

942122

EPAS1
Endothelial PAS domain-containing protein 1

1

20

Small-scale

0.479

High

942123

PCGF1
Polycomb group RING finger protein 1

1

20

High-throughput

0.479

High

942125

BRD7
Bromodomain-containing protein 7

1

20

High-throughput

0.479

High

942126

CHD7
Chromodomain-helicase-DNA-binding protein 7

1

20

Small-scale

0.479

High

942127

TRPS1
Zinc finger transcription factor Trps1

1

20

High-throughput

0.479

High

942128

ZN608
Zinc finger protein 608

1

18

High-throughput

0.479

High

942130

ZN281
Zinc finger protein 281

1

15

High-throughput

0.479

High

942132

NCOR2
Nuclear receptor corepressor 2

1

20

High-throughput

0.479

High

942133

NCOA3
Nuclear receptor coactivator 3

1

20

High-throughput

0.479

High

942119

OTUB2
Ubiquitin thioesterase OTUB2

1

0

Small-scale

0.458

High

942087

SUMO1
Small ubiquitin-related modifier 1

1

11

Small-scale

0.445

High

942110

PRSR1
Proline and serine-rich protein 1

1

20

High-throughput

0.437

High

942105

CJ055
Uncharacterized protein C10orf55

2

0

High-throughput

0.316

High

137204

EXOC5
Exocyst complex component 5

1

0

High-throughput

0.282

High


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Last updated: 11Aug2025