HitPredict

Interactor 1: LIPA1 (Q13136)
Liprin-alpha-1 (LAR-interacting protein 1) (LIP-1) (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1)
Gene: PPFIA1

Interactor 2: RIMS1 (Q86UR5)
Regulating synaptic membrane exocytosis protein 1 (Rab-3-interacting molecule 1) (RIM 1) (Rab-3-interacting protein 2)
Gene: RIMS1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	37207277
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	PDZ~SAM_1
Common GO terms	GO:0005829 - cytosol GO:0048786 - presynaptic active zone
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1202 Hs			1 1692
+	Hs
		259649 LIPA2_HUMAN (35-1202): 3.45e-130: 431: 62.82		RIMS1_HUMAN (1-1692): 0: 972: 100.00
+	Hs
		724903 MYH9_HUMAN (177-857): 4.68e-24: 112: 15.37		RIMS1_HUMAN (1-1692): 0: 972: 100.00
+	Hs
		255248 LIPA3_HUMAN (1-265): 3.37e-12: 73.2: 12.45		RIMS1_HUMAN (1-1692): 0: 972: 100.00
+	Hs
		725194 MYH10_HUMAN (320-813): 7.13e-10: 66: 11.29		RIMS1_HUMAN (1-1692): 0: 972: 100.00
+	Hs
		128891 MY18A_HUMAN (1-565): 4.66e-28: 125: 13.27		P3C2A_HUMAN (1538-1664): 1.27e-23: 111: 27.48
+	Hs
		128818 MYH9_HUMAN (177-857): 4.68e-24: 112: 15.37		P3C2A_HUMAN (1538-1664): 1.27e-23: 111: 27.48
+	Hs
		522636 MYH7_HUMAN (153-902): 1.92e-36: 152: 13.40		SYT3_HUMAN (744-864): 1.76e-09: 64.7: 36.29
+	Hs
		277815 MYH3_HUMAN (1-547): 1.77e-21: 104: 13.20		DYSF_HUMAN (1553-1686): 1.03e-14: 82.3: 20.00
+	Dm
		114424 M9PCD4_DROME (3-277): 4.35e-10: 66.3: 12.59		Q9VEE5_DROME (300-867): 6.29e-19: 96.1: 16.12
+	Dm
		114422 M9PCD4_DROME (3-277): 4.35e-10: 66.3: 12.59		Q9V483_DROME (1458-1669): 3.3e-11: 70.8: 16.74
+	Hs
		1309697 MYH4_HUMAN (461-886): 4.97e-11: 69.7: 7.67		SYT3_HUMAN (744-864): 1.76e-09: 64.7: 36.29