HitPredict

Interactor 1: CAND1 (Q86VP6)
Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and neddylation-dissociated protein 1) (TBP-interacting protein of 120 kDa A) (TBP-interacting protein 120A) (p120 CAND1)
Gene: CAND1

Interactor 2: DCNL1 (Q96GG9)
DCN1-like protein 1 (DCNL1) (DCUN1 domain-containing protein 1) (Defective in cullin neddylation protein 1-like protein 1) (Squamous cell carcinoma-related oncogene)
Gene: DCUN1D1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.94	0.60	0.753

Property	Details
Experiments	29499133, 18826954, 25411243, 25349211, 26906416, 30587576, 21145461, 24192928
Identification Methods	pull down, affinity chromatography technology, tandem affinity purification
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000151 - ubiquitin ligase complex GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1230 Hs			1 259
+	Hs
		1161489 CAND1_HUMAN (1-1230): 0: 922: 100.00		DCNL2_HUMAN (1-257): 3.46e-130: 370: 78.21
+	Hs
		1202023 CAND1_HUMAN (1-1230): 0: 922: 100.00		DCNL4_HUMAN (42-250): 9.75e-90: 269: 31.10
+	Hs
		1201975 CAND1_HUMAN (1-1230): 0: 922: 100.00		DCNL3_HUMAN (54-250): 7.87e-85: 257: 41.58
+	Hs
		1202086 CAND1_HUMAN (1-1230): 0: 922: 100.00		DCNL5_HUMAN (55-248): 1.36e-85: 256: 34.02