HitPredict

Interactor 1: CBX3 (Q13185)
Chromobox protein homolog 3 (HECH) (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein)
Gene: CBX3

Interactor 2: EP400 (Q96L91)
E1A-binding protein p400 (EC 3.6.4.-) (CAG repeat protein 32) (Domino homolog) (hDomino) (Trinucleotide repeat-containing gene 12 protein) (p400 kDa SWI2/SNF2-related protein)
Gene: EP400

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Chromo~SNF2-rel_dom
Common GO terms	GO:0003682 - chromatin binding GO:0005654 - nucleoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 183 Hs			1 3159
+	Hs
		229384 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		SMCA5_HUMAN (970-1548): 0: 629: 21.71
+	Hs
		658667 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		SMCA1_HUMAN (938-1627): 0: 623: 19.83
+	Hs
		658650 CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33		SMCA1_HUMAN (938-1627): 0: 623: 19.83
+	Hs
		1027145 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		CHD5_HUMAN (1501-2524): 1.9e-162: 558: 13.68
+	Hs
		1027026 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		CHD9_HUMAN (1565-2538): 3.24e-144: 509: 13.41
+	Hs
		1027277 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		CHD8_HUMAN (1521-2397): 1.55e-138: 490: 13.07
+	Dm
		399035 HP1_DROME (9-180): 2.12e-45: 150: 38.73		INO80_DROME (1887-2145): 3.88e-75: 281: 26.92
+	Hs
		1027257 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		SMRCD_HUMAN (1895-2052): 1.85e-24: 115: 38.27
+	Hs
		1027300 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		CHD7_HUMAN (2-514): 7.31e-12: 74.1: 10.60
+	Hs
		846954 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		SMCA4_HUMAN (2622-2971): 9.21e-09: 63.7: 10.17
+	Hs
		800319 CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89		SMCA2_HUMAN (2772-3070): 2.99e-09: 65.3: 11.65
+	Hs
		800320 CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89		SMCA4_HUMAN (2622-2971): 9.21e-09: 63.7: 10.17
+	Hs
		846745 CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33		SMCA2_HUMAN (2772-3070): 2.99e-09: 65.3: 11.65
+	Hs
		846923 CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33		SMCA4_HUMAN (2622-2971): 9.21e-09: 63.7: 10.17
+	Hs
		847118 CDYL_HUMAN (16-165): 6.53e-34: 127: 25.16		SMCA4_HUMAN (2622-2971): 9.21e-09: 63.7: 10.17
+	Hs
		123332 CBX4_HUMAN (21-121): 4.95e-27: 108: 29.52		CHD7_HUMAN (2-514): 7.31e-12: 74.1: 10.60