HitPredict

Interactor 1: SPTCB (Q00963)
Spectrin beta chain
Gene: beta-Spec

Interactor 2: CHM4 (Q8T0Q4)
Charged multivesicular body protein 4 (CHMP4) (ESCRT-III complex core component shrb) (Protein Shrub)
Gene: shrb

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	38944040
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0045169 - fusome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2291 Dm			1 226
+	Hs
		1028839 SPTB2_HUMAN (1-2262): 0: 630: 54.97		CHM4C_HUMAN (1-226): 2.9e-42: 144: 48.50
+	Hs
		1028871 SPTB2_HUMAN (1-2262): 0: 630: 54.97		CHM4B_HUMAN (1-225): 1.24e-38: 134: 56.96
+	Hs
		224776 ACTN4_HUMAN (49-741): 4.05e-121: 409: 37.40		CHM4C_HUMAN (1-226): 2.9e-42: 144: 48.50
+	Hs
		224797 ACTN4_HUMAN (49-741): 4.05e-121: 409: 37.40		CHM4B_HUMAN (1-225): 1.24e-38: 134: 56.96
+	Hs
		555738 ACTN1_HUMAN (22-772): 4.19e-89: 314: 32.47		CHM4C_HUMAN (1-226): 2.9e-42: 144: 48.50
+	Hs
		555756 ACTN1_HUMAN (22-772): 4.19e-89: 314: 32.47		CHM4B_HUMAN (1-225): 1.24e-38: 134: 56.96
+	Hs
		1061543 ACTN3_HUMAN (37-773): 3.71e-83: 296: 32.41		CHM4C_HUMAN (1-226): 2.9e-42: 144: 48.50
+	Hs
		1061556 ACTN3_HUMAN (37-773): 3.71e-83: 296: 32.41		CHM4B_HUMAN (1-225): 1.24e-38: 134: 56.96
+	Hs
		1117438 SPTN1_HUMAN (915-2281): 9.49e-59: 228: 19.52		CHM4C_HUMAN (1-226): 2.9e-42: 144: 48.50
+	Hs
		1117478 SPTN1_HUMAN (915-2281): 9.49e-59: 228: 19.52		CHM4B_HUMAN (1-225): 1.24e-38: 134: 56.96
+	Hs
		1143265 PLEC_HUMAN (370-2161): 3.61e-47: 190: 9.32		CHM4B_HUMAN (1-225): 1.24e-38: 134: 56.96
+	Hs
		174794 SPTN2_HUMAN (940-2280): 4.53e-31: 136: 14.59		CHM4C_HUMAN (1-226): 2.9e-42: 144: 48.50
+	Hs
		1385862 SPTN4_HUMAN (295-2279): 1.58e-30: 135: 15.54		CHM4C_HUMAN (1-226): 2.9e-42: 144: 48.50
+	Hs
		174806 SPTN2_HUMAN (940-2280): 4.53e-31: 136: 14.59		CHM4B_HUMAN (1-225): 1.24e-38: 134: 56.96
+	Hs
		1431490 SPTN4_HUMAN (295-2279): 1.58e-30: 135: 15.54		CHM4B_HUMAN (1-225): 1.24e-38: 134: 56.96
+	Hs
		1385921 MACF1_HUMAN (1280-2137): 1.91e-13: 79.1: 13.10		CHM4C_HUMAN (1-226): 2.9e-42: 144: 48.50
+	Hs
		773772 ACTN2_HUMAN (609-867): 4.41e-11: 70.5: 23.24		CHM4C_HUMAN (1-226): 2.9e-42: 144: 48.50
+	Hs
		540265 SPTB1_HUMAN (1772-2283): 2.11e-09: 65.5: 14.89		CHM4C_HUMAN (1-226): 2.9e-42: 144: 48.50
+	Hs
		773782 ACTN2_HUMAN (609-867): 4.41e-11: 70.5: 23.24		CHM4B_HUMAN (1-225): 1.24e-38: 134: 56.96
+	Hs
		540275 SPTB1_HUMAN (1772-2283): 2.11e-09: 65.5: 14.89		CHM4B_HUMAN (1-225): 1.24e-38: 134: 56.96