HitPredict

Interactor 1: SRSF5 (Q13243)
Serine/arginine-rich splicing factor 5 (Delayed-early protein HRS) (Pre-mRNA-splicing factor SRP40) (Splicing factor, arginine/serine-rich 5)
Gene: SRSF5

Interactor 2: DDX24 (Q9GZR7)
ATP-dependent RNA helicase DDX24 (EC 3.6.4.13) (DEAD box protein 24)
Gene: DDX24

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	33961781, 35864588, 34349018
Identification Methods	affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005730 - nucleolus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 272 Hs			1 859
+	Hs
		992921 SRSF1_HUMAN (2-170): 6.55e-57: 184: 43.68		DDX24_HUMAN (1-859): 8.65e-159: 487: 100.00
+	Hs
		993826 SRSF4_HUMAN (5-265): 3.78e-51: 176: 53.64		DDX24_HUMAN (1-859): 8.65e-159: 487: 100.00
+	Hs
		1029084 SRSF6_HUMAN (5-184): 1.35e-48: 165: 61.96		DDX24_HUMAN (1-859): 8.65e-159: 487: 100.00
+	Hs
		1314614 RBM4_HUMAN (3-122): 5.32e-17: 81.7: 22.50		DDX24_HUMAN (1-859): 8.65e-159: 487: 100.00
+	Sc
		376792 PABP_YEAST (86-192): 7.08e-15: 75.9: 19.64		DHH1_YEAST (287-742): 6.34e-140: 426: 24.57
+	Hs
		134018 PABP4_HUMAN (104-189): 3.45e-16: 80.1: 21.98		DDX3X_HUMAN (158-723): 2.85e-123: 388: 19.08
+	Hs
		133858 PABP1_HUMAN (98-189): 1.16e-15: 78.6: 18.56		DDX3X_HUMAN (158-723): 2.85e-123: 388: 19.08
+	Hs
		571581 RBM4_HUMAN (3-122): 5.32e-17: 81.7: 22.50		DDX5_HUMAN (232-774): 1.14e-121: 382: 19.89
+	Sc
		376580 PABP_YEAST (86-192): 7.08e-15: 75.9: 19.64		DED1_YEAST (255-734): 7.5e-120: 377: 23.74
+	Hs
		992985 SRSF1_HUMAN (2-170): 6.55e-57: 184: 43.68		DDX41_HUMAN (390-691): 7.07e-32: 134: 31.17
+	Hs
		1028843 SRSF5_HUMAN (1-240): 2.63e-54: 178: 100.00		DDX18_HUMAN (391-740): 1.22e-32: 137: 29.69
+	Hs
		1028866 SRSF5_HUMAN (1-240): 2.63e-54: 178: 100.00		DDX41_HUMAN (390-691): 7.07e-32: 134: 31.17
+	Sc
		376755 PABP_YEAST (86-192): 7.08e-15: 75.9: 19.64		MAK5_YEAST (385-811): 2.71e-65: 235: 33.13
+	Hs
		993864 SRSF4_HUMAN (5-265): 3.78e-51: 176: 53.64		DDX41_HUMAN (390-691): 7.07e-32: 134: 31.17
+	Hs
		1028630 SRSF9_HUMAN (2-211): 1.47e-52: 172: 33.02		DDX41_HUMAN (390-691): 7.07e-32: 134: 31.17
+	Hs
		1029127 SRSF6_HUMAN (5-184): 1.35e-48: 165: 61.96		DDX18_HUMAN (391-740): 1.22e-32: 137: 29.69
+	Hs
		1029151 SRSF6_HUMAN (5-184): 1.35e-48: 165: 61.96		DDX41_HUMAN (390-691): 7.07e-32: 134: 31.17
+	Mm
		1208005 RBM4_MOUSE (2-122): 2.58e-17: 82.4: 21.49		DDX18_MOUSE (381-740): 8.81e-32: 134: 29.43
+	Hs
		1271643 RBM4_HUMAN (3-122): 5.32e-17: 81.7: 22.50		DDX17_HUMAN (130-267): 9.12e-12: 70.9: 21.43
+	Mm
		857323 TIA1_MOUSE (2-101): 7.98e-13: 69.3: 15.69		DDX17_MOUSE (130-267): 1.79e-11: 69.7: 21.43