HitPredict

Interactor 1: SRSF6 (Q13247)
Serine/arginine-rich splicing factor 6 (Pre-mRNA-splicing factor SRP55) (Splicing factor, arginine/serine-rich 6)
Gene: SRSF6

Interactor 2: RBP56 (Q92804)
TATA-binding protein-associated factor 2N (68 kDa TATA-binding protein-associated factor) (TAF(II)68) (TAFII68) (RNA-binding protein 56)
Gene: TAF15

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29884807
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 344 Hs			1 592
+	Hs
		992865 SRSF1_HUMAN (3-188): 3.02e-54: 180: 36.65		RBP56_HUMAN (1-394): 3.45e-37: 148: 100.00
+	Hs
		967128 SRSF1_HUMAN (3-188): 3.02e-54: 180: 36.65		EWS_HUMAN (4-383): 3.73e-35: 142: 32.96
+	Hs
		726769 SRSF1_HUMAN (3-188): 3.02e-54: 180: 36.65		FUS_HUMAN (8-381): 2.72e-32: 132: 39.28
+	Mm
		1207139 SRSF9_MOUSE (3-222): 3.56e-49: 166: 35.11		Q8BQ46_MOUSE (1-394): 3.73e-35: 141: 94.16
+	Hs
		967148 SRSF9_HUMAN (3-222): 5.6e-49: 165: 34.22		EWS_HUMAN (4-383): 3.73e-35: 142: 32.96
+	Hs
		967129 SRSF4_HUMAN (1-323): 1.85e-45: 163: 63.47		EWS_HUMAN (4-383): 3.73e-35: 142: 32.96
+	Hs
		726791 SRSF9_HUMAN (3-222): 5.6e-49: 165: 34.22		FUS_HUMAN (8-381): 2.72e-32: 132: 39.28
+	Mm
		1207135 RBM4_MOUSE (1-343): 1.34e-43: 155: 18.18		Q8BQ46_MOUSE (1-394): 3.73e-35: 141: 94.16
+	Hs
		967149 SRSF6_HUMAN (1-323): 3.2e-43: 154: 100.00		EWS_HUMAN (4-383): 3.73e-35: 142: 32.96
+	Hs
		993005 SRSF1_HUMAN (3-188): 3.02e-54: 180: 36.65		RBMX2_HUMAN (227-440): 6.24e-28: 116: 19.36
+	Hs
		212132 SRSF4_HUMAN (1-323): 1.85e-45: 163: 63.47		HTSF1_HUMAN (113-325): 5.58e-31: 130: 18.06
+	Hs
		726792 SRSF5_HUMAN (2-180): 3.02e-46: 160: 64.25		FUS_HUMAN (8-381): 2.72e-32: 132: 39.28
+	Hs
		726793 SRSF6_HUMAN (1-323): 3.2e-43: 154: 100.00		FUS_HUMAN (8-381): 2.72e-32: 132: 39.28
+	Hs
		1028881 SRSF5_HUMAN (2-180): 3.02e-46: 160: 64.25		RBMX2_HUMAN (227-440): 6.24e-28: 116: 19.36
+	Hs
		1308809 RBM4B_HUMAN (1-343): 2.62e-45: 160: 18.23		RBMX2_HUMAN (227-440): 6.24e-28: 116: 19.36
+	Mm
		857328 TIA1_MOUSE (2-335): 1.54e-33: 129: 15.46		EWS_MOUSE (4-383): 9.82e-32: 132: 33.26
+	Hs
		1031411 PABP4_HUMAN (101-191): 1.26e-12: 70.7: 21.88		RBP56_HUMAN (1-394): 3.45e-37: 148: 100.00
+	Hs
		726795 PABP4_HUMAN (101-191): 1.26e-12: 70.7: 21.88		FUS_HUMAN (8-381): 2.72e-32: 132: 39.28
+	Hs
		516383 PABP1_HUMAN (101-191): 1.28e-11: 67.6: 19.79		FUS_HUMAN (8-381): 2.72e-32: 132: 39.28
+	Hs
		1347058 RBM28_HUMAN (4-248): 1.53e-12: 70.6: 14.61		RBMX2_HUMAN (227-440): 6.24e-28: 116: 19.36