HitPredict

Interactor 1: SRSF6 (Q13247)
Serine/arginine-rich splicing factor 6 (Pre-mRNA-splicing factor SRP55) (Splicing factor, arginine/serine-rich 6)
Gene: SRSF6

Interactor 2: GTPB4 (Q9BZE4)
GTP-binding protein 4 (Chronic renal failure gene protein) (GTP-binding protein NGB) (Nucleolar GTP-binding protein 1)
Gene: GTPBP4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 344 Hs			1 634
+	Hs
		992917 SRSF1_HUMAN (3-188): 3.02e-54: 180: 36.65		GTPB4_HUMAN (1-634): 0: 688: 100.00
+	Hs
		1314612 RBM4_HUMAN (1-343): 1.17e-47: 166: 17.05		GTPB4_HUMAN (1-634): 0: 688: 100.00
+	Hs
		1028806 SRSF5_HUMAN (2-180): 3.02e-46: 160: 64.25		GTPB4_HUMAN (1-634): 0: 688: 100.00
+	Hs
		1308760 RBM4B_HUMAN (1-343): 2.62e-45: 160: 18.23		GTPB4_HUMAN (1-634): 0: 688: 100.00
+	Hs
		59589 SRSF5_HUMAN (2-180): 3.02e-46: 160: 64.25		GTPBA_HUMAN (168-358): 1.81e-41: 156: 20.09
+	Hs
		1031500 PABP4_HUMAN (101-191): 1.26e-12: 70.7: 21.88		DRG1_HUMAN (99-366): 3.24e-61: 209: 16.79
+	Hs
		1347056 RBM28_HUMAN (4-248): 1.53e-12: 70.6: 14.61		DRG1_HUMAN (99-366): 3.24e-61: 209: 16.79
+	Hs
		516753 PABP1_HUMAN (101-191): 1.28e-11: 67.6: 19.79		DRG1_HUMAN (99-366): 3.24e-61: 209: 16.79
+	Sc
		633972 GBP2_YEAST (4-203): 4.8e-23: 100: 19.05		RBG2_YEAST (102-356): 1.66e-45: 167: 19.78
+	Sc
		376872 PABP_YEAST (99-194): 1.33e-11: 67.6: 19.80		RBG2_YEAST (102-356): 1.66e-45: 167: 19.78
+	Hs
		1331139 RBM28_HUMAN (4-248): 1.53e-12: 70.6: 14.61		MTG2_HUMAN (148-343): 1.48e-43: 163: 23.04