HitPredict

Interactor 1: NMDE3 (Q01098)
Glutamate receptor ionotropic, NMDA 2C (GluN2C) (Glutamate [NMDA] receptor subunit epsilon-3) (N-methyl D-aspartate receptor subtype 2C) (NMDAR2C) (NR2C)
Gene: Grin2c

Interactor 2: EPS8 (Q08509)
Epidermal growth factor receptor kinase substrate 8
Gene: EPS8

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17018287
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0017146 - NMDA selective glutamate receptor complex GO:0098978 - glutamatergic synapse
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1239 Mm			1 821
+	Mm
		771416 NMDE1_MOUSE (3-954): 0: 776: 53.48		EPS8_MOUSE (1-821): 0: 975: 100.00
+	Mm
		663024 GRIA1_MOUSE (7-870): 0: 672: 21.98		EPS8_MOUSE (1-821): 0: 975: 100.00
+	Mm
		771467 NMDZ1_MOUSE (9-933): 0: 651: 23.54		EPS8_MOUSE (1-821): 0: 975: 100.00
+	Hs
		440532 NMDE2_HUMAN (9-943): 0: 821: 52.92		FYN_HUMAN (455-593): 1.73e-30: 128: 16.31
+	Mm
		813511 NMDE2_MOUSE (9-943): 0: 814: 52.70		FYN_MOUSE (455-593): 4.03e-30: 127: 16.31
+	Mm
		771409 NMDE1_MOUSE (3-954): 0: 776: 53.48		FYN_MOUSE (455-593): 4.03e-30: 127: 16.31
+	Hs
		440518 NMDE1_HUMAN (4-954): 0: 763: 53.69		FYN_HUMAN (455-593): 1.73e-30: 128: 16.31
+	Hs
		189312 NMDE4_HUMAN (30-866): 0: 668: 62.99		CRK_HUMAN (394-701): 7.23e-39: 148: 11.00
+	Hs
		440504 NMDZ1_HUMAN (9-933): 0: 649: 23.54		FYN_HUMAN (455-593): 1.73e-30: 128: 16.31