HitPredict

Interactor 1: NMDE1 (P35436)
Glutamate receptor ionotropic, NMDA 2A (GluN2A) (Glutamate [NMDA] receptor subunit epsilon-1) (N-methyl D-aspartate receptor subtype 2A) (NMDAR2A) (NR2A)
Gene: Grin2a

Interactor 2: EPS8 (Q08509)
Epidermal growth factor receptor kinase substrate 8
Gene: EPS8

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17018287
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0014069 - postsynaptic density GO:0017146 - NMDA selective glutamate receptor complex GO:0045202 - synapse GO:0098978 - glutamatergic synapse
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1464 Mm			1 821
+	Mm
		771409 NMDE1_MOUSE (1-1464): 0: 1793: 100.00		FYN_MOUSE (455-593): 4.03e-30: 127: 16.31
+	Hs
		440518 NMDE1_HUMAN (1-1464): 0: 1704: 95.29		FYN_HUMAN (455-593): 1.73e-30: 128: 16.31
+	Mm
		1029257 NMDE3_MOUSE (1-939): 0: 802: 54.28		EPS8_MOUSE (1-821): 0: 975: 100.00
+	Mm
		663024 GRIA1_MOUSE (13-905): 0: 708: 18.97		EPS8_MOUSE (1-821): 0: 975: 100.00
+	Mm
		771467 NMDZ1_MOUSE (6-940): 0: 691: 23.29		EPS8_MOUSE (1-821): 0: 975: 100.00
+	Mm
		813511 NMDE2_MOUSE (13-1464): 0: 1527: 53.30		FYN_MOUSE (455-593): 4.03e-30: 127: 16.31
+	Hs
		440532 NMDE2_HUMAN (13-1464): 0: 1515: 53.29		FYN_HUMAN (455-593): 1.73e-30: 128: 16.31
+	Hs
		189312 NMDE4_HUMAN (12-872): 0: 699: 55.84		CRK_HUMAN (394-701): 7.23e-39: 148: 11.00
+	Hs
		440504 NMDZ1_HUMAN (6-940): 0: 688: 23.40		FYN_HUMAN (455-593): 1.73e-30: 128: 16.31