HitPredict

Interactor 1: CTBP1 (Q13363)
C-terminal-binding protein 1 (CtBP1) (EC 1.1.1.-)
Gene: CTBP1

Interactor 2: TRPS1 (Q9UHF7)
Zinc finger transcription factor Trps1 (Tricho-rhino-phalangeal syndrome type I protein) (Zinc finger protein GC79)
Gene: TRPS1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.89	0.60	0.732

Property	Details
Experiments	26186194, 28514442, 33961781, 35271311, 35016035, 31041561
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II GO:0019904 - protein domain specific binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 440 Hs			1 1281
+	Hs
		881324 CTBP2_HUMAN (10-439): 0: 538: 80.23		TRPS1_HUMAN (1-1281): 0: 1888: 100.00
+	Hs
		1032385 CTBP1_HUMAN (1-440): 0: 547: 100.00		IKZF1_HUMAN (781-1272): 5.18e-107: 349: 19.45
+	Hs
		881163 CTBP2_HUMAN (10-439): 0: 538: 80.23		IKZF1_HUMAN (781-1272): 5.18e-107: 349: 19.45
+	Rn
		88975 CTBP1_RAT (14-440): 0: 526: 98.36		D4A9W4_RAT (781-1272): 4.82e-97: 323: 17.76
+	Hs
		1032673 CTBP1_HUMAN (1-440): 0: 547: 100.00		IKZF2_HUMAN (800-1270): 2.98e-84: 287: 16.20
+	Hs
		881332 CTBP2_HUMAN (10-439): 0: 538: 80.23		IKZF2_HUMAN (800-1270): 2.98e-84: 287: 16.20
+	Hs
		1032605 CTBP1_HUMAN (1-440): 0: 547: 100.00		IKZF4_HUMAN (771-1268): 1.19e-79: 276: 18.47
+	Hs
		881333 CTBP2_HUMAN (10-439): 0: 538: 80.23		IKZF3_HUMAN (850-1268): 4.38e-82: 280: 18.63
+	Hs
		798822 CTBP2_HUMAN (10-439): 0: 538: 80.23		GATA4_HUMAN (870-1060): 3.74e-45: 171: 28.36