HitPredict

Interactor 1: EWS (Q01844)
RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint region 1 protein)
Gene: EWSR1

Interactor 2: IF4H (Q15056)
Eukaryotic translation initiation factor 4H (eIF-4H) (Williams-Beuren syndrome chromosomal region 1 protein)
Gene: EIF4H

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24999758
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1, RRM_1~zf-RanBP
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 656 Hs			1 248
+	Hs
		726754 EWS_HUMAN (1-656): 1.53e-47: 179: 100.00		TIA1_HUMAN (36-231): 7.81e-34: 127: 13.64
+	Hs
		550392 RBP56_HUMAN (109-555): 5.81e-53: 193: 35.05		PABP1_HUMAN (33-237): 3.61e-27: 111: 14.49
+	Hs
		1102042 RBP56_HUMAN (109-555): 5.81e-53: 193: 35.05		PABP4_HUMAN (33-219): 3.99e-24: 102: 13.54
+	Mm
		915302 EWS_MOUSE (1-656): 4.64e-42: 163: 94.06		TIA1_MOUSE (36-231): 8.23e-34: 127: 13.64
+	Hs
		1127052 RBP56_HUMAN (109-555): 5.81e-53: 193: 35.05		RBM39_HUMAN (21-248): 5.32e-22: 96.3: 13.10
+	Hs
		1032961 EWS_HUMAN (1-656): 1.53e-47: 179: 100.00		ELAV3_HUMAN (42-122): 2.25e-23: 98.6: 25.30
+	Hs
		686612 EWS_HUMAN (1-656): 1.53e-47: 179: 100.00		ELAV4_HUMAN (41-123): 2.45e-22: 95.9: 25.88
+	Hs
		341553 EYA4_HUMAN (3-271): 6.1e-39: 154: 18.02		TIAR_HUMAN (36-248): 1.47e-31: 120: 11.63
+	Mm
		953827 Q8BQ46_MOUSE (109-555): 4.72e-53: 193: 35.35		CIRBP_MOUSE (45-196): 1.97e-13: 68.3: 27.92
+	Hs
		750405 EWS_HUMAN (1-656): 1.53e-47: 179: 100.00		CSTF2_HUMAN (44-133): 3.73e-13: 70.2: 29.35
+	Hs
		550147 FUS_HUMAN (55-545): 1.16e-31: 131: 30.35		PABP1_HUMAN (33-237): 3.61e-27: 111: 14.49
+	Hs
		775060 FUS_HUMAN (55-545): 1.16e-31: 131: 30.35		PABP4_HUMAN (33-219): 3.99e-24: 102: 13.54
+	Hs
		775081 FUS_HUMAN (55-545): 1.16e-31: 131: 30.35		RBM39_HUMAN (21-248): 5.32e-22: 96.3: 13.10
+	Hs
		750393 FUS_HUMAN (55-545): 1.16e-31: 131: 30.35		CSTF2_HUMAN (44-133): 3.73e-13: 70.2: 29.35