HitPredict

Interactor 1: EWS (Q01844)
RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint region 1 protein)
Gene: EWSR1

Interactor 2: TF7L2 (Q9NQB0)
Transcription factor 7-like 2 (HMG box transcription factor 4) (T-cell-specific transcription factor 4) (T-cell factor 4) (TCF-4) (hTCF-4)
Gene: TCF7L2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27684187
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 656 Hs			1 619
+	Hs
		775325 FUS_HUMAN (55-545): 1.16e-31: 131: 30.35		TF7L2_HUMAN (1-619): 3.12e-84: 277: 100.00
+	Hs
		1033192 EWS_HUMAN (1-656): 1.53e-47: 179: 100.00		SOX7_HUMAN (317-610): 5.87e-44: 163: 18.27
+	Hs
		1033167 EWS_HUMAN (1-656): 1.53e-47: 179: 100.00		CIC_HUMAN (32-578): 2.48e-34: 142: 15.58
+	Hs
		776055 EWS_HUMAN (1-656): 1.53e-47: 179: 100.00		SOX5_HUMAN (16-483): 2.31e-34: 141: 12.50
+	Hs
		1065338 RBP56_HUMAN (109-555): 5.81e-53: 193: 35.05		SSRP1_HUMAN (333-511): 5.9e-26: 115: 18.89
+	Hs
		872597 RBP56_HUMAN (109-555): 5.81e-53: 193: 35.05		SOX2_HUMAN (311-614): 4.16e-26: 111: 15.39
+	Hs
		341654 EYA4_HUMAN (3-271): 6.1e-39: 154: 18.02		CIC_HUMAN (32-578): 2.48e-34: 142: 15.58
+	Hs
		872217 EWS_HUMAN (1-656): 1.53e-47: 179: 100.00		SOX2_HUMAN (311-614): 4.16e-26: 111: 15.39
+	Mm
		872976 EYA1_MOUSE (3-277): 2.58e-40: 157: 22.50		SOX2_MOUSE (318-613): 3.22e-33: 131: 14.15
+	Hs
		551909 CO6A3_HUMAN (3-318): 2.28e-37: 152: 11.24		SOX2_HUMAN (311-614): 4.16e-26: 111: 15.39
+	Hs
		1033338 EWS_HUMAN (1-656): 1.53e-47: 179: 100.00		PCLO_HUMAN (22-610): 1.57e-12: 73.1: 10.59
+	Hs
		774912 FUS_HUMAN (55-545): 1.16e-31: 131: 30.35		SOX2_HUMAN (311-614): 4.16e-26: 111: 15.39
+	Hs
		186646 EWS_HUMAN (1-656): 1.53e-47: 179: 100.00		HMGB3_HUMAN (354-493): 5.02e-09: 58.4: 14.79
+	Hs
		124642 EYA2_HUMAN (27-278): 1.49e-18: 91.3: 20.16		CIC_HUMAN (32-578): 2.48e-34: 142: 15.58
+	Hs
		551733 COBA1_HUMAN (2-522): 4.6e-20: 97.6: 11.51		SOX2_HUMAN (311-614): 4.16e-26: 111: 15.39
+	Ce
		602187 CO4A1_CAEEL (3-259): 9.35e-15: 80.6: 8.46		POP1_CAEEL (237-566): 2.56e-30: 126: 25.63