HitPredict

Interactor 1: IKZF1 (Q13422)
DNA-binding protein Ikaros (Ikaros family zinc finger protein 1) (Lymphoid transcription factor LyF-1)
Gene: IKZF1

Interactor 2: WDR26 (Q9H7D7)
WD repeat-containing protein 26 (CUL4- and DDB1-associated WDR protein 2) (Myocardial ischemic preconditioning up-regulated protein 2)
Gene: WDR26

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 519 Hs			1 661
+	Hs
		1033649 IKZF1_HUMAN (1-519): 0: 664: 100.00		TAF5_HUMAN (450-661): 8.05e-55: 202: 14.58
+	Hs
		1033662 IKZF1_HUMAN (1-519): 0: 664: 100.00		A16L1_HUMAN (522-652): 1.81e-24: 110: 18.94
+	Hs
		1033684 IKZF1_HUMAN (1-519): 0: 664: 100.00		POC1B_HUMAN (70-392): 1.31e-14: 78.6: 12.96
+	Hs
		1033680 IKZF1_HUMAN (1-519): 0: 664: 100.00		POC1A_HUMAN (61-383): 1.79e-14: 77.9: 12.00
+	Hs
		1074813 IKZF3_HUMAN (11-515): 4.42e-139: 413: 53.82		TAF5_HUMAN (450-661): 8.05e-55: 202: 14.58
+	Hs
		1146946 IKZF3_HUMAN (11-515): 4.42e-139: 413: 53.82		A16L1_HUMAN (522-652): 1.81e-24: 110: 18.94
+	Mm
		140047 IKZF3_MOUSE (13-515): 1.73e-144: 426: 53.70		A16L1_MOUSE (356-473): 6.39e-15: 80.1: 19.67
+	Mm
		1207579 Q8C5P6_MOUSE (1-254): 8.48e-111: 331: 94.88		A16L1_MOUSE (356-473): 6.39e-15: 80.1: 19.67
+	Mm
		925840 ZN322_MOUSE (135-224): 1.27e-12: 71.6: 38.89		LIS1_MOUSE (394-661): 7.74e-78: 255: 15.23