Interactor 1: MSH3 (P25336)
DNA mismatch repair protein MSH3 (Mismatch-binding protein) (MBP) (MutS protein homolog 3)
Gene: MSH3

Interactor 2: MSH2 (P25847)
DNA mismatch repair protein MSH2 (MutS protein homolog 2)
Gene: MSH2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.975

The method score is based on:

Property Details
Experiments 8805366, 8600025, 16429126, 37968396, 8910404, 17720936, 24403070, 24550389, 24746922, 24811092
Identification Methods biochemical, coimmunoprecipitation, affinity chromatography technology, pull down, two hybrid, ion exchange chromatography, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains MutS_I~MutS_I, MutS_I~MutS_II, MutS_I~MutS_III, MutS_I~MutS_V, MutS_II~MutS_III, MutS_II~MutS_V, MutS_III~MutS_III, MutS_III~MutS_V, MutS_V~MutS_V
Common GO terms GO:0000406 - double-strand/single-strand DNA junction binding
GO:0000710 - meiotic mismatch repair
GO:0000735 - removal of nonhomologous ends
GO:0005524 - ATP binding
GO:0005634 - nucleus
and 7 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 1018
Sc

1 964
+ Hs
+ Mm
+ Sc
+ Dr
+ Hs
+ Hs
+ Sc
+ At
+ At
+ Ce
+ Ec
+ At

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Last updated: 15 Jul 2024