Interactor 1: XRCC4 (Q13426)
DNA repair protein XRCC4 (hXRCC4) (X-ray repair cross-complementing protein 4) [Cleaved into: Protein XRCC4, C-terminus (XRCC4/C)]
Gene: XRCC4
Interactor 2: NHEJ1 (Q9H9Q4)
Non-homologous end-joining factor 1 (Protein cernunnos) (XRCC4-like factor)
Gene: NHEJ1
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 0.90 | 0.925 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 17567543, 26774286, 29997244, 30017584, 21768349, 21070942, 16439205, 18064046, 21349273 |
| Identification Methods | two hybrid, affinity chromatography technology, fluorescent resonance energy transfer, molecular sieving, isothermal titration calorimetry, transmission electron microscopy, light scattering, x ray scattering, x-ray crystallography, anti bait coimmunoprecipitation and 3 others
more... |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | XLF~XRCC4 |
| Common GO terms | GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005958 - DNA-dependent protein kinase-DNA ligase 4 complex GO:0006303 - double-strand break repair via nonhomologous end joining GO:0032807 - DNA ligase IV complex and 5 others more... |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
