Protein: I5P2
Type II inositol 1,4,5-trisphosphate 5-phosphatase (EC 3.1.3.36) (75 kDa inositol polyphosphate-5-phosphatase) (Phosphoinositide 5-phosphatase) (5PTase)

Gene: I5P2, INPP5B
Organism: Homo sapiens
Interactions: 22
UniProt ID: P32019

Gene Ontology (top 5):
GO:0001701 - in utero embryonic development
GO:0004439 - phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
GO:0005737 - cytoplasm
GO:0005793 - endoplasmic reticulum-Golgi intermediate compartment
GO:0005794 - Golgi apparatus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

731951

OCRL
Inositol polyphosphate 5-phosphatase OCRL

2

4

High-throughput

0.811

High

731949

RAB8A
Ras-related protein Rab-8A

2

9

Small-scale

0.712

High

731952

SESQ2
Sesquipedalian-2

2

9

High-throughput

0.628

High

731955

SESQ1
Sesquipedalian-1

2

10

High-throughput

0.628

High

631086

RAB5A
Ras-related protein Rab-5A

1

13

High-throughput

0.618

High

731947

RAB9A
Ras-related protein Rab-9A

1

11

High-throughput

0.618

High

330692

KI20A
Kinesin-like protein KIF20A

1

4

High-throughput

0.536

High

731948

JAK3
Tyrosine-protein kinase JAK3

1

20

High-throughput

0.536

High

731958

NUF2
Kinetochore protein Nuf2

1

6

High-throughput

0.536

High

292894

RNH2A
Ribonuclease H2 subunit A

1

0

High-throughput

0.513

High

341905

CEP43
Centrosomal protein 43

1

0

High-throughput

0.513

High

731956

IMP2L
Mitochondrial inner membrane protease subunit 2

1

0

High-throughput

0.513

High

731957

PAR6B
Partitioning defective 6 homolog beta

1

0

High-throughput

0.513

High

421582

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.501

High

731960

DJC11
DnaJ homolog subfamily C member 11

1

5

High-throughput

0.489

High

240876

PRKN
E3 ubiquitin-protein ligase parkin

1

7

High-throughput

0.479

High

731950

ARF6
ADP-ribosylation factor 6

1

7

High-throughput

0.479

High

731953

TRI67
Tripartite motif-containing protein 67

1

7

High-throughput

0.479

High

731954

ATG9A
Autophagy-related protein 9A

1

2

High-throughput

0.479

High

731959

SAR1A
Small COPII coat GTPase SAR1A

1

12

High-throughput

0.479

High

731961

SAR1B
Small COPII coat GTPase SAR1B

1

9

High-throughput

0.479

High

429380

JUN
Transcription factor Jun

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025