Interactor 1: RAB5A (P20339)
Ras-related protein Rab-5A (EC 3.6.5.2)
Gene: RAB5A
Interactor 2: OCRL (Q01968)
Inositol polyphosphate 5-phosphatase OCRL (EC 3.1.3.36) (EC 3.1.3.56) (Inositol polyphosphate 5-phosphatase OCRL-1) (OCRL-1) (Lowe oculocerebrorenal syndrome protein) (Phosphatidylinositol 3,4,5-triphosphate 5-phosphatase) (EC 3.1.3.86)
Gene: OCRL
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.92 | 1.00 | 0.962 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 16902405, 32203420, 19795375, 34079125, 25107275, unassigned2213, 21378754 |
| Identification Methods | pull down, affinity chromatography technology, two hybrid, proximity labelling technology, anti tag coimmunoprecipitation, fluorescence polarization spectroscopy, enzyme linked immunosorbent assay, molecular sieving |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | OCRL-like_ASH~Ras, Ras~RhoGAP |
| Common GO terms | GO:0005737 - cytoplasm GO:0005769 - early endosome GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0030670 - phagocytic vesicle membrane and 1 others more... |
| Homologous interactions | 13 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
