HitPredict

Interactor 1: BIRC2 (Q13490)
Baculoviral IAP repeat-containing protein 2 (EC 2.3.2.27) (Cellular inhibitor of apoptosis 1) (C-IAP1) (IAP homolog B) (Inhibitor of apoptosis protein 2) (hIAP-2) (hIAP2) (RING finger protein 48) (RING-type E3 ubiquitin transferase BIRC2) (TNFR2-TRAF-signaling complex protein 2)
Gene: BIRC2

Interactor 2: RNF31 (Q96EP0)
E3 ubiquitin-protein ligase RNF31 (EC 2.3.2.31) (HOIL-1-interacting protein) (HOIP) (RING finger protein 31) (RING-type E3 ubiquitin transferase RNF31) (Zinc in-between-RING-finger ubiquitin-associated domain protein)
Gene: RNF31

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 0.60 0.694

The method score is based on:

Property Details
Experiments 30561431, 23524849, 27545878, 24726327
Identification Methods affinity chromatography technology, virotrap, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000209 - protein polyubiquitination
GO:0004842 - ubiquitin-protein transferase activity
GO:0005829 - cytosol
GO:0008270 - zinc ion binding
GO:0009898 - cytoplasmic side of plasma membrane
and 5 others

more...
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 618
Hs

1 1072
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+ Dr

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Last updated: 15 Jul 2024