Protein: RCC1L
RCC1-like G exchanging factor-like protein (RCC1-like protein) (Williams-Beuren syndrome chromosomal region 16 protein)

Gene: RCC1L
Organism: Homo sapiens
Interactions: 106
UniProt ID: Q96I51

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005525 - GTP binding
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

281135

NDK6
Nucleoside diphosphate kinase 6

6

3

Small-scale

0.727

High

350958

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

4

1

Small-scale

0.686

High

1394088

GOLP3
Golgi phosphoprotein 3

4

0

High-throughput

0.661

High

1015681

RHOG
Rho-related GTP-binding protein RhoG

1

5

High-throughput

0.618

High

1394075

RCC1L
RCC1-like G exchanging factor-like protein

1

14

High-throughput

0.618

High

1385998

RUSD4
Pseudouridylate synthase RPUSD4, mitochondrial

2

1

Small-scale

0.611

High

135315

IF2B3
Insulin-like growth factor 2 mRNA-binding protein 3

2

5

High-throughput

0.601

High

1009286

PRR3
Proline-rich protein 3

2

1

High-throughput

0.601

High

1394082

RM13
Large ribosomal subunit protein uL13m

2

2

High-throughput

0.601

High

1394102

YBOX2
Y-box-binding protein 2

2

5

High-throughput

0.601

High

1123383

ICT1
Large ribosomal subunit protein mL62

2

0

High-throughput

0.585

High

242590

PRKN
E3 ubiquitin-protein ligase parkin

2

12

High-throughput

0.584

High

1381676

FAKD4
FAST kinase domain-containing protein 4

2

2

Small-scale

0.584

High

1394094

FAKD2
FAST kinase domain-containing protein 2, mitochondrial

2

2

Small-scale

0.584

High

1394096

MRES1
Mitochondrial transcription rescue factor 1

2

1

High-throughput

0.584

High

1196141

RM51
Large ribosomal subunit protein mL51

2

0

High-throughput

0.576

High

1213316

RM02
Large ribosomal subunit protein uL2m

2

0

High-throughput

0.576

High

1394092

NGRN
Neugrin

2

0

Small-scale

0.559

High

799394

BRCA1
Breast cancer type 1 susceptibility protein

1

6

High-throughput

0.552

High

927489

ATX1
Ataxin-1

1

2

High-throughput

0.541

High

48055

RBM47
RNA-binding protein 47

1

3

High-throughput

0.536

High

271087

PTCD1
Pentatricopeptide repeat-containing protein 1, mitochondrial

1

1

High-throughput

0.536

High

786215

LONM
Lon protease homolog, mitochondrial

1

2

High-throughput

0.536

High

1089508

ILF2
Interleukin enhancer-binding factor 2

1

1

High-throughput

0.536

High

1148761

RBMS2
RNA-binding motif, single-stranded-interacting protein 2

1

5

High-throughput

0.536

High

1160042

SRSF7
Serine/arginine-rich splicing factor 7

1

5

High-throughput

0.536

High

1162490

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

1

High-throughput

0.536

High

1349531

RM30
Large ribosomal subunit protein uL30m

1

1

High-throughput

0.536

High

1388367

MTEF3
Transcription termination factor 3, mitochondrial

1

1

High-throughput

0.536

High

1394078

RBM42
RNA-binding protein 42

1

2

High-throughput

0.536

High

1394080

SELO
Protein adenylyltransferase SelO, mitochondrial

1

1

High-throughput

0.536

High

1394085

PAIP1
Polyadenylate-binding protein-interacting protein 1

1

2

High-throughput

0.536

High

1394091

LN28A
Protein lin-28 homolog A

1

5

High-throughput

0.536

High

1394099

ZN346
Zinc finger protein 346

1

1

High-throughput

0.536

High

1394100

ABT1
Activator of basal transcription 1

1

1

High-throughput

0.536

High

966739

1433G
14-3-3 protein gamma

1

5

High-throughput

0.515

High

177582

MRPP3
Mitochondrial ribonuclease P catalytic subunit

1

0

High-throughput

0.513

High

554825

ODBA
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial

1

0

High-throughput

0.513

High

891010

NDUV1
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial

1

0

High-throughput

0.513

High

984904

RL31
Large ribosomal subunit protein eL31

1

0

High-throughput

0.513

High

1309071

FABD
Malonyl-CoA-acyl carrier protein transacylase, mitochondrial

1

0

High-throughput

0.513

High

1328261

RM50
Large ribosomal subunit protein mL50

1

0

High-throughput

0.513

High

1347043

G45IP
Large ribosomal subunit protein mL64

1

0

High-throughput

0.513

High

1394083

RM04
Large ribosomal subunit protein uL4m

1

0

High-throughput

0.513

High

1394101

RT17
Small ribosomal subunit protein uS17m

1

0

High-throughput

0.513

High

1394103

SYYM
Tyrosine--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

1279886

RBBP6
E3 ubiquitin-protein ligase RBBP6

1

7

High-throughput

0.508

High

338933

CBX6
Chromobox protein homolog 6

1

4

High-throughput

0.489

High

1251037

RBMS3
RNA-binding motif, single-stranded-interacting protein 3

1

5

High-throughput

0.489

High

1311154

UBR2
E3 ubiquitin-protein ligase UBR2

1

2

High-throughput

0.489

High

229552

NRDC
Nardilysin

1

3

High-throughput

0.479

High

282046

MPPB
Mitochondrial-processing peptidase subunit beta

1

3

High-throughput

0.479

High

401304

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

7

High-throughput

0.479

High

560902

HEM1
5-aminolevulinate synthase, non-specific, mitochondrial

1

1

High-throughput

0.479

High

666342

THIL
Acetyl-CoA acetyltransferase, mitochondrial

1

1

High-throughput

0.479

High

841880

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

2

High-throughput

0.479

High

888737

ACOT2
Acyl-coenzyme A thioesterase 2, mitochondrial

1

1

High-throughput

0.479

High

1048643

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

1

High-throughput

0.479

High

1083707

MPPA
Mitochondrial-processing peptidase subunit alpha

1

3

High-throughput

0.479

High

1092624

ECH1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

1

5

High-throughput

0.479

High

1117808

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

5

High-throughput

0.479

High

1240318

RUSD3
Mitochondrial mRNA pseudouridine synthase RPUSD3

1

1

Small-scale

0.479

High

1287635

ACOT1
Acyl-coenzyme A thioesterase 1

1

1

High-throughput

0.479

High

1392763

COQ2
4-hydroxybenzoate polyprenyltransferase, mitochondrial

1

1

High-throughput

0.479

High

1394077

EFGM
Elongation factor G, mitochondrial

1

3

High-throughput

0.479

High

1394084

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

20

High-throughput

0.479

High

1394086

CLPB
Mitochondrial disaggregase

1

1

High-throughput

0.479

High

1139800

SETB1
Histone-lysine N-methyltransferase SETDB1

1

3

High-throughput

0.470

High

1347353

LMO3
LIM domain only protein 3

1

2

High-throughput

0.470

High

1371238

KAT5
Histone acetyltransferase KAT5

1

1

High-throughput

0.470

High

61978

GTPBA
GTP-binding protein 10

1

0

Small-scale

0.458

High

71754

NUD19
Acyl-coenzyme A diphosphatase NUDT19

1

0

High-throughput

0.458

High

183706

RT12
Small ribosomal subunit protein uS12m

1

0

High-throughput

0.458

High

1217795

ANGE2
Protein angel homolog 2

1

0

High-throughput

0.458

High

1234686

ETFR1
Electron transfer flavoprotein regulatory factor 1

1

0

High-throughput

0.458

High

1293594

HOGA1
4-hydroxy-2-oxoglutarate aldolase, mitochondrial

1

0

High-throughput

0.458

High

1388239

RRFM
Ribosome-recycling factor, mitochondrial

1

0

High-throughput

0.458

High

1394076

TEFM
Transcription elongation factor, mitochondrial

1

0

Small-scale

0.458

High

1394079

DHRS4
Dehydrogenase/reductase SDR family member 4

1

0

High-throughput

0.458

High

1394081

RM20
Large ribosomal subunit protein bL20m

1

0

Small-scale

0.458

High

1394087

MTRFR
Mitochondrial translation release factor in rescue

1

0

High-throughput

0.458

High

1394090

MET17
Ribosome assembly protein METTL17, mitochondrial

1

0

High-throughput

0.458

High

1394093

STAR7
StAR-related lipid transfer protein 7, mitochondrial

1

0

High-throughput

0.458

High

1394098

ATIF1
ATPase inhibitor, mitochondrial

1

0

High-throughput

0.458

High

1394104

RM11
Large ribosomal subunit protein uL11m

1

0

High-throughput

0.458

High

1394105

AFG32
Mitochondrial inner membrane m-AAA protease component AFG3L2

1

0

High-throughput

0.458

High

485339

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

2

High-throughput

0.445

High

653507

HEMH
Ferrochelatase, mitochondrial

1

2

High-throughput

0.445

High

1016567

SRSF3
Serine/arginine-rich splicing factor 3

1

7

High-throughput

0.445

High

76245

B4DJ38
Pentatricopeptide repeat-containing protein 1, mitochondrial

1

1

High-throughput

0.437

High

315887

RECQ4
ATP-dependent DNA helicase Q4

1

8

High-throughput

0.437

High

406508

MYCN
N-myc proto-oncogene protein

1

6

High-throughput

0.437

High

879364

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

2

High-throughput

0.437

High

1140694

KIF14
Kinesin-like protein KIF14

1

5

High-throughput

0.437

High

1255073

TRI67
Tripartite motif-containing protein 67

1

7

High-throughput

0.437

High

1333188

AFG2A
ATPase family gene 2 protein homolog A

1

4

High-throughput

0.437

High

1368568

KAT6A
Histone acetyltransferase KAT6A

1

5

High-throughput

0.437

High

1394089

PKHA4
Pleckstrin homology domain-containing family A member 4

1

8

High-throughput

0.437

High

1394097

ZRAN1
Ubiquitin thioesterase ZRANB1

1

9

High-throughput

0.437

High

1323712

THEM5
Acyl-coenzyme A thioesterase THEM5

1

0

High-throughput

0.426

High

1394095

F120A
Constitutive coactivator of PPAR-gamma-like protein 1

1

0

High-throughput

0.426

High

214139

DHH
Desert hedgehog protein

2

0

High-throughput

0.328

High

1187301

PIGY
Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y

1

0

High-throughput

0.279

Low

106461

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

431597

AP2A
Transcription factor AP-2-alpha

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025