HitPredict

Interactor 1: ID2 (Q02363)
DNA-binding protein inhibitor ID-2 (Class B basic helix-loop-helix protein 26) (bHLHb26) (Inhibitor of DNA binding 2) (Inhibitor of differentiation 2)
Gene: ID2

Interactor 2: OLIG1 (Q8TAK6)
Oligodendrocyte transcription factor 1 (Oligo1) (Class B basic helix-loop-helix protein 6) (bHLHb6) (Class E basic helix-loop-helix protein 21) (bHLHe21)
Gene: OLIG1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	15280210
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	HLH~HLH
Common GO terms	GO:0005634 - nucleus GO:0014003 - oligodendrocyte development GO:0046983 - protein dimerization activity GO:0048663 - neuron fate commitment
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 134 Hs			1 271
+	Mm
		832355 ID2_MOUSE (1-134): 1.14e-70: 209: 98.51		OLIG1_MOUSE (1-271): 1.47e-54: 178: 82.66
+	Hs
		561209 ID2_HUMAN (1-134): 1.83e-70: 209: 100.00		MYF5_HUMAN (69-264): 1.32e-33: 124: 14.83
+	Hs
		1036511 ID2_HUMAN (1-134): 1.83e-70: 209: 100.00		OLIG2_HUMAN (41-254): 4.47e-32: 122: 32.39
+	Mm
		832354 ID2_MOUSE (1-134): 1.14e-70: 209: 98.51		OLIG2_MOUSE (41-254): 2.09e-30: 117: 31.98
+	Hs
		868652 ID4_HUMAN (33-109): 7.06e-31: 109: 54.12		OLIG1_HUMAN (1-271): 1.67e-58: 189: 100.00
+	Mm
		832358 ID4_MOUSE (33-109): 1.74e-30: 108: 54.12		OLIG1_MOUSE (1-271): 1.47e-54: 178: 82.66
+	Hs
		561208 ID1_HUMAN (14-133): 1.58e-45: 146: 45.39		MYF5_HUMAN (69-264): 1.32e-33: 124: 14.83
+	Hs
		561210 ID3_HUMAN (1-133): 8.42e-44: 141: 39.13		MYF5_HUMAN (69-264): 1.32e-33: 124: 14.83
+	Hs
		581756 ID1_HUMAN (14-133): 1.58e-45: 146: 45.39		MYOG_HUMAN (32-236): 3.81e-30: 114: 16.67
+	Mm
		627913 ID1_MOUSE (15-123): 2.98e-41: 136: 50.00		TAL1_MOUSE (21-254): 2.29e-26: 107: 20.09
+	Hs
		868647 ID4_HUMAN (33-109): 7.06e-31: 109: 54.12		OLIG2_HUMAN (41-254): 4.47e-32: 122: 32.39
+	Mm
		832357 ID4_MOUSE (33-109): 1.74e-30: 108: 54.12		OLIG2_MOUSE (41-254): 2.09e-30: 117: 31.98
+	Hs
		581757 ID4_HUMAN (33-109): 7.06e-31: 109: 54.12		MYOG_HUMAN (32-236): 3.81e-30: 114: 16.67
+	Hs
		868657 ID4_HUMAN (33-109): 7.06e-31: 109: 54.12		NGN3_HUMAN (40-228): 1.51e-27: 107: 22.55
+	Hs
		605178 ID4_HUMAN (33-109): 7.06e-31: 109: 54.12		TAL1_HUMAN (17-254): 3.64e-26: 106: 18.33
+	Hs
		658502 ID4_HUMAN (33-109): 7.06e-31: 109: 54.12		MYF6_HUMAN (22-206): 7.2e-26: 103: 18.62