Protein: ID4
DNA-binding protein inhibitor ID-4 (Class B basic helix-loop-helix protein 27) (bHLHb27) (Inhibitor of DNA binding 4) (Inhibitor of differentiation 4)

Gene: ID4
Organism: Homo sapiens
Interactions: 25
UniProt ID: P47928

Gene Ontology (top 5):
GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001649 - osteoblast differentiation
GO:0002052 - positive regulation of neuroblast proliferation
GO:0003714 - transcription corepressor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

587024

ITF2
Transcription factor 4

4

20

High-throughput

0.892

High

581757

MYOG
Myogenin

2

19

High-throughput

0.811

High

658502

MYF6
Myogenic factor 6

2

20

High-throughput

0.811

High

868646

ID2
DNA-binding protein inhibitor ID-2

2

4

High-throughput

0.811

High

868657

NGN3
Neurogenin-3

2

20

High-throughput

0.811

High

605178

TAL1
T-cell acute lymphocytic leukemia protein 1

2

20

High-throughput

0.798

High

587426

TFE2
Transcription factor E2-alpha

2

20

Small-scale

0.754

High

65874

MSGN1
Mesogenin-1

1

16

High-throughput

0.691

High

868650

FIGLA
Factor in the germline alpha

1

15

High-throughput

0.691

High

868655

ASCL3
Achaete-scute homolog 3

1

20

High-throughput

0.691

High

558968

LYL1
Protein lyl-1

1

20

High-throughput

0.618

High

868647

OLIG2
Oligodendrocyte transcription factor 2

1

17

Small-scale

0.618

High

868652

OLIG1
Oligodendrocyte transcription factor 1

1

16

Small-scale

0.618

High

868654

HTF4
Transcription factor 12

1

20

Small-scale

0.618

High

868653

MET2A
tRNA N(3)-cytidine methyltransferase METTL2A

2

0

High-throughput

0.602

High

868656

FZR1
Fizzy-related protein homolog

2

4

Small-scale

0.584

High

868651

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

2

High-throughput

0.515

High

593942

NCK1
SH2/SH3 adapter protein NCK1

1

4

High-throughput

0.479

High

855553

CRK
Adapter molecule crk

1

3

High-throughput

0.479

High

868645

GRB2
Growth factor receptor-bound protein 2

1

3

High-throughput

0.479

High

557172

SRC
Proto-oncogene tyrosine-protein kinase Src

1

0

High-throughput

0.458

High

619007

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

0

High-throughput

0.458

High

699644

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

0

High-throughput

0.458

High

868648

CUL3
Cullin-3

1

0

High-throughput

0.458

High

868649

RN123
E3 ubiquitin-protein ligase RNF123

1

0

High-throughput

0.458

High


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Last updated: 11Aug2025