Interactor 1: HDAC1 (Q13547)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Interactor 2: HDAC1 (Q13547)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 1.00 0.931

The method score is based on:

Property Details
Experiments 12920132, 31980649, 34709266, 21258344, 23752268, 9150135
Identification Methods affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Hist_deacetyl~Hist_deacetyl
Common GO terms GO:0000118 - histone deacetylase complex
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000792 - heterochromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
and 64 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 482
Hs

1 482
+ Mm
+ Mm
+ Hs
+ Hs
+ Mm
+ Rn
+ Hs
+ Dm
+ Sc
+ Hs
+ Hs
+ Hs
+ Sp
+ Hs
+ At

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Last updated: 15 Jul 2024