HitPredict

Interactor 1: HDAC1 (Q13547)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Interactor 2: SMRCD (Q9H4L7)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.4.12) (ATP-dependent helicase 1) (hHEL1)
Gene: SMARCAD1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21549307
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000792 - heterochromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006338 - chromatin remodeling
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 482 Hs			1 1026
+	Hs
		1270443 HDAC2_HUMAN (1-478): 0: 666: 85.92		SMRCD_HUMAN (1-1026): 0: 903: 100.00
+	Mm
		140261 HDAC1_MOUSE (1-482): 0: 672: 99.38		SMCA4_MOUSE (96-1024): 0: 692: 26.43
+	Hs
		846962 HDAC1_HUMAN (1-482): 0: 668: 100.00		SMCA4_HUMAN (96-1024): 0: 693: 26.54
+	Hs
		847037 HDAC2_HUMAN (1-478): 0: 666: 85.92		SMCA4_HUMAN (96-1024): 0: 693: 26.54
+	Hs
		846768 HDAC1_HUMAN (1-482): 0: 668: 100.00		SMCA2_HUMAN (55-1024): 0: 689: 25.05
+	Mm
		936385 HDAC2_MOUSE (1-478): 0: 664: 85.71		SMCA4_MOUSE (96-1024): 0: 692: 26.43
+	Hs
		846833 HDAC2_HUMAN (1-478): 0: 666: 85.92		SMCA2_HUMAN (55-1024): 0: 689: 25.05
+	Hs
		1038730 HDAC1_HUMAN (1-482): 0: 668: 100.00		CHD8_HUMAN (181-1021): 0: 641: 23.28
+	Hs
		1038563 HDAC1_HUMAN (1-482): 0: 668: 100.00		CHD5_HUMAN (338-1022): 0: 629: 27.78
+	Hs
		1255037 HDAC2_HUMAN (1-478): 0: 666: 85.92		CHD5_HUMAN (338-1022): 0: 629: 27.78
+	Hs
		1018465 HDAC1_HUMAN (1-482): 0: 668: 100.00		CHD3_HUMAN (338-1022): 0: 621: 27.64
+	Mm
		56897 HDAC1_MOUSE (1-482): 0: 672: 99.38		CHD5_MOUSE (338-1022): 0: 616: 27.78
+	Hs
		1018617 HDAC2_HUMAN (1-478): 0: 666: 85.92		CHD3_HUMAN (338-1022): 0: 621: 27.64
+	Mm
		56900 HDAC2_MOUSE (1-478): 0: 664: 85.71		CHD5_MOUSE (338-1022): 0: 616: 27.78
+	Dm
		332806 HDAC1_DROME (6-477): 0: 658: 77.33		CHDM_DROME (486-1021): 0: 607: 31.84
+	Hs
		976446 HDAC1_HUMAN (1-482): 0: 668: 100.00		ERCC6_HUMAN (21-1021): 0: 595: 20.53
+	Hs
		976489 HDAC2_HUMAN (1-478): 0: 666: 85.92		ERCC6_HUMAN (21-1021): 0: 595: 20.53
+	Hs
		229453 HDAC2_HUMAN (1-478): 0: 666: 85.92		SMCA5_HUMAN (353-1021): 0: 594: 29.60
+	Hs
		1038748 HDAC1_HUMAN (1-482): 0: 668: 100.00		HELLS_HUMAN (479-999): 1.2e-93: 318: 37.59
+	Hs
		1270466 HDAC2_HUMAN (1-478): 0: 666: 85.92		HELLS_HUMAN (479-999): 1.2e-93: 318: 37.59