HitPredict

Interactor 1: KPCZ (Q02956)
Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)
Gene: Prkcz

Interactor 2: SQSTM (Q64337)
Sequestosome-1 (STONE14) (Ubiquitin-binding protein p62)
Gene: Sqstm1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	26773517
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PB1~PB1, PB1~Pkinase
Common GO terms	GO:0005829 - cytosol GO:0008270 - zinc ion binding
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 592 Mm			1 442
+	Rn
		148005 KPCZ_RAT (1-592): 0: 671: 98.99		SQSTM_RAT (1-442): 0: 762: 97.06
+	Rn
		98879 KPCI_RAT (1-592): 0: 646: 69.54		SQSTM_RAT (1-442): 0: 762: 97.06
+	Hs
		1051223 KPCZ_HUMAN (1-592): 0: 657: 95.61		SQSTM_HUMAN (1-442): 0: 715: 89.82
+	Hs
		835664 KPCI_HUMAN (1-592): 0: 645: 69.37		SQSTM_HUMAN (1-442): 0: 715: 89.82
+	Mm
		705875 KPCD_MOUSE (68-586): 8.17e-176: 515: 33.65		SQSTM_MOUSE (1-442): 0: 777: 100.00
+	Hs
		1051920 KPCD_HUMAN (10-586): 4.98e-175: 513: 31.51		SQSTM_HUMAN (1-442): 0: 715: 89.82
+	Hs
		1107758 PKN1_HUMAN (10-583): 2.91e-161: 486: 24.24		SQSTM_HUMAN (1-442): 0: 715: 89.82
+	Hs
		658602 KS6B1_HUMAN (227-590): 2.58e-145: 432: 35.60		SQSTM_HUMAN (1-442): 0: 715: 89.82
+	Rn
		148004 KPCE_RAT (6-203): 1.58e-34: 141: 19.05		SQSTM_RAT (1-442): 0: 762: 97.06
+	Rn
		148017 KPCL_RAT (6-185): 5.09e-31: 130: 24.61		SQSTM_RAT (1-442): 0: 762: 97.06
+	Rn
		148013 KPCB_RAT (101-181): 2.08e-17: 88: 30.86		SQSTM_RAT (1-442): 0: 762: 97.06
+	Rn
		148003 KPCD_RAT (5-172): 9.55e-16: 82.7: 14.37		SQSTM_RAT (1-442): 0: 762: 97.06
+	Rn
		148012 KPCG_RAT (116-180): 2.05e-10: 65.9: 36.92		SQSTM_RAT (1-442): 0: 762: 97.06
+	Dm
		56111 APKC_DROME (3-592): 0: 611: 61.32		REF2P_DROME (112-173): 2.25e-18: 89.4: 41.27