HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: SHKB1 (Q8TBC3)
SH3KBP1-binding protein 1 (SETA-binding protein 1)
Gene: SHKBP1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.92	0.50	0.678

Property	Details
Experiments	28963344, 32296183, 35563538, 21145461, 21988832, unassigned1304, 34591642
Identification Methods	pull down, two hybrid, affinity chromatography technology, tandem affinity purification, two hybrid array, validated two hybrid, two hybrid prey pooling approach, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 768 Hs			1 707
+	Hs
		1042934 CUL3_HUMAN (1-768): 0: 951: 100.00		KCTD3_HUMAN (3-657): 0: 992: 63.58
+	Hs
		1041705 CUL3_HUMAN (1-768): 0: 951: 100.00		KCD21_HUMAN (17-207): 5.08e-52: 182: 29.95
+	Hs
		1042309 CUL3_HUMAN (1-768): 0: 951: 100.00		KCTD7_HUMAN (2-228): 4.8e-46: 167: 27.16
+	Hs
		1042523 CUL3_HUMAN (1-768): 0: 951: 100.00		BACD3_HUMAN (1-200): 5.07e-42: 157: 24.26
+	Hs
		1042165 CUL3_HUMAN (1-768): 0: 951: 100.00		BACD1_HUMAN (5-162): 6.2e-40: 151: 27.50
+	Hs
		1041533 CUL3_HUMAN (1-768): 0: 951: 100.00		BACD2_HUMAN (2-162): 2.53e-38: 146: 25.15
+	Hs
		1041881 CUL3_HUMAN (1-768): 0: 951: 100.00		KCTD1_HUMAN (2-156): 1.08e-38: 145: 25.77
+	Hs
		1042675 CUL3_HUMAN (1-768): 0: 951: 100.00		KCTD5_HUMAN (4-127): 2.47e-37: 141: 35.43
+	Hs
		1041891 CUL3_HUMAN (1-768): 0: 951: 100.00		KCTD9_HUMAN (17-173): 2.07e-35: 140: 28.92
+	Hs
		1041584 CUL3_HUMAN (1-768): 0: 951: 100.00		KCTD2_HUMAN (13-124): 2.17e-36: 139: 41.53
+	Hs
		1042035 CUL3_HUMAN (1-768): 0: 951: 100.00		KCD17_HUMAN (19-118): 8.5e-35: 136: 45.10
+	Hs
		1042063 CUL3_HUMAN (1-768): 0: 951: 100.00		KCTD6_HUMAN (17-112): 9.65e-30: 119: 41.84
+	Dm
		1213854 Q8IP45_DROME (17-768): 0: 868: 69.08		Q9W579_DROME (7-129): 1.45e-37: 140: 35.20
+	Ce
		184054 CUL3_CAEEL (4-768): 0: 792: 48.08		O16612_CAEEL (17-193): 3.38e-44: 159: 24.58
+	Ce
		954547 CUL3_CAEEL (4-768): 0: 792: 48.08		P91563_CAEEL (17-185): 2.38e-41: 152: 28.65
+	Ce
		1088887 CUL3_CAEEL (4-768): 0: 792: 48.08		Q965M5_CAEEL (16-150): 1.21e-38: 144: 33.58
+	Ce
		1088878 CUL3_CAEEL (4-768): 0: 792: 48.08		Q18776_CAEEL (2-125): 2.6e-36: 139: 37.01
+	Ce
		1088879 CUL3_CAEEL (4-768): 0: 792: 48.08		Q18986_CAEEL (17-117): 1.22e-36: 139: 34.95
+	Ce
		109385 CUL3_CAEEL (4-768): 0: 792: 48.08		H2KY83_CAEEL (17-119): 4.27e-34: 130: 32.38
+	Hs
		1041480 CUL2_HUMAN (30-768): 0: 672: 26.17		KCTD5_HUMAN (4-127): 2.47e-37: 141: 35.43