HitPredict

Interactor 1: HAS1 (Q03532)
ATP-dependent RNA helicase HAS1 (EC 3.6.4.13) (Helicase associated with SET1 protein 1)
Gene: HAS1

Interactor 2: BRX1 (Q08235)
Ribosome biogenesis protein BRX1
Gene: BRX1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.686

Property	Details
Experiments	30568249, 31511893, 16429126, 37968396
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005730 - nucleolus GO:0030687 - preribosome, large subunit precursor
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 505 Sc			1 291
+	Sc
		666558 DBP2_YEAST (5-421): 2.01e-132: 396: 29.22		BRX1_YEAST (1-291): 1.12e-99: 295: 100.00
+	Sc
		632659 DBP4_YEAST (3-501): 5.54e-165: 487: 37.70		RPF2_YEAST (6-282): 1.45e-61: 199: 16.84
+	Sc
		632716 DBP4_YEAST (3-501): 5.54e-165: 487: 37.70		IMP4_YEAST (5-261): 1.74e-61: 198: 17.76
+	Sc
		782428 HAS1_YEAST (1-505): 9.17e-165: 477: 100.00		RPF2_YEAST (6-282): 1.45e-61: 199: 16.84
+	Sc
		925187 HAS1_YEAST (1-505): 9.17e-165: 477: 100.00		IMP4_YEAST (5-261): 1.74e-61: 198: 17.76
+	Dm
		1471269 DDX18_DROME (8-500): 4.3e-135: 407: 58.59		BRX1_DROME (8-291): 5.4e-82: 253: 40.91
+	Sc
		805084 HAS1_YEAST (1-505): 9.17e-165: 477: 100.00		RPF1_YEAST (4-252): 5.86e-52: 173: 14.40
+	Sc
		804650 HAS1_YEAST (1-505): 9.17e-165: 477: 100.00		SSF1_YEAST (10-197): 9.09e-34: 129: 15.64
+	Sc
		1043314 HAS1_YEAST (1-505): 9.17e-165: 477: 100.00		SSF2_YEAST (10-197): 8.36e-33: 127: 15.17
+	Dm
		1471247 DDX18_DROME (8-500): 4.3e-135: 407: 58.59		RPF1_DROME (12-252): 5.75e-53: 179: 17.07
+	Hs
		1446765 DDX18_HUMAN (2-492): 2.67e-138: 415: 59.76		SSF1_HUMAN (12-281): 5.7e-45: 160: 12.87
+	Sc
		444510 DED1_YEAST (20-418): 3.6e-138: 413: 27.85		SSF1_YEAST (10-197): 9.09e-34: 129: 15.64
+	Sc
		746684 DRS1_YEAST (26-394): 3.81e-72: 245: 38.32		BRX1_YEAST (1-291): 1.12e-99: 295: 100.00
+	Dm
		1471234 DDX18_DROME (8-500): 4.3e-135: 407: 58.59		PPAN_DROME (6-248): 5.22e-26: 108: 13.77
+	Dm
		1477480 DDX47_DROME (15-392): 6.59e-71: 236: 39.43		BRX1_DROME (8-291): 5.4e-82: 253: 40.91
+	Sc
		746614 DRS1_YEAST (26-394): 3.81e-72: 245: 38.32		RPF2_YEAST (6-282): 1.45e-61: 199: 16.84
+	Sc
		746624 DRS1_YEAST (26-394): 3.81e-72: 245: 38.32		RPF1_YEAST (4-252): 5.86e-52: 173: 14.40
+	Hs
		1392241 DDX27_HUMAN (44-441): 6.78e-71: 242: 37.04		SSF1_HUMAN (12-281): 5.7e-45: 160: 12.87
+	Sc
		746623 DRS1_YEAST (26-394): 3.81e-72: 245: 38.32		SSF1_YEAST (10-197): 9.09e-34: 129: 15.64
+	Sc
		746693 DRS1_YEAST (26-394): 3.81e-72: 245: 38.32		SSF2_YEAST (10-197): 8.36e-33: 127: 15.17