HitPredict

Interactor 1: F5H823 (F5H823)
RAP1B, member of RAS oncogene family
Gene: RAP1B

Interactor 2: NEK10 (Q6ZWH5)
Serine/threonine-protein kinase Nek10 (EC 2.7.11.1) (Never in mitosis A-related kinase 10) (NimA-related protein kinase 10)
Gene: NEK10

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	32368190
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Pkinase~Ras
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 103 Hs			1 1172
+	Hs
		373798 RASN_HUMAN (1-101): 6.91e-47: 150: 49.51		AKT1_HUMAN (384-840): 1.02e-142: 441: 20.09
+	Hs
		375224 RASK_HUMAN (1-101): 2.62e-47: 151: 50.50		AKT2_HUMAN (384-834): 3.04e-141: 437: 20.31
+	Hs
		375197 RASK_HUMAN (1-101): 2.62e-47: 151: 50.50		MARK3_HUMAN (474-1160): 1.08e-131: 421: 18.52
+	Hs
		373785 RASN_HUMAN (1-101): 6.91e-47: 150: 49.51		MARK3_HUMAN (474-1160): 1.08e-131: 421: 18.52
+	Hs
		728571 RAB2A_HUMAN (1-102): 1.49e-40: 134: 37.26		AKT2_HUMAN (384-834): 3.04e-141: 437: 20.31
+	Hs
		374415 RASH_HUMAN (1-101): 2.9e-43: 140: 50.50		MARK3_HUMAN (474-1160): 1.08e-131: 421: 18.52
+	Hs
		692025 RAB2A_HUMAN (1-102): 1.49e-40: 134: 37.26		MARK3_HUMAN (474-1160): 1.08e-131: 421: 18.52
+	Hs
		959438 RAP2B_HUMAN (1-100): 1.51e-34: 118: 57.00		KCC2B_HUMAN (513-1022): 2.99e-116: 377: 21.36
+	Hs
		959370 RAP1B_HUMAN (1-103): 5.19e-43: 140: 100.00		NEK7_HUMAN (516-779): 7.34e-46: 169: 33.71
+	Sc
		376201 RAS2_YEAST (1-100): 3.15e-43: 144: 55.00		KAPA_YEAST (518-773): 1.19e-28: 121: 32.81