HitPredict

Interactor 1: SPTN1 (Q13813)
Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain) (Spectrin, non-erythroid alpha subunit)
Gene: SPTAN1

Interactor 2: ANLN (Q9NQW6)
Anillin
Gene: ANLN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.827

Property	Details
Experiments	26496610, 31586073, 36526897
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~SH3_1
Common GO terms	GO:0003779 - actin binding GO:0005829 - cytosol GO:0045296 - cadherin binding
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 2472 Hs			1 1124
+	Hs
		164668 SPTN2_HUMAN (141-1932): 1.25e-65: 250: 20.41		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		963430 SPTB2_HUMAN (2-1043): 1.4e-42: 174: 20.52		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		1059276 GOGB1_HUMAN (2-1186): 3.65e-38: 160: 10.57		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		974153 DYST_HUMAN (5-2410): 1.41e-35: 152: 10.59		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		1068674 PLEC_HUMAN (16-1253): 4.4e-31: 137: 9.18		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		1329040 SPTN4_HUMAN (961-2371): 1.09e-21: 105: 13.80		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		1343798 MACF1_HUMAN (9-1261): 9.1e-18: 93.6: 12.48		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		506845 SPTB1_HUMAN (1743-2409): 3.32e-13: 78.1: 19.70		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		828628 CENPF_HUMAN (1723-2444): 8.12e-13: 77: 9.28		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		521622 ACTN1_HUMAN (1862-2210): 3.16e-11: 71.2: 22.25		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		211670 ACTN4_HUMAN (1843-2219): 1.15e-09: 66.2: 20.15		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Dm
		527106 SPTCA_DROME (3-2472): 1.26e-174: 598: 63.92		ANLN_DROME (542-1112): 1.6e-160: 511: 29.84