HitPredict

Interactor 1: PKP1 (Q13835)
Plakophilin-1 (Band 6 protein) (B6P)
Gene: PKP1

Interactor 2: MYOME (Q5VU43)
Myomegalin (Cardiomyopathy-associated protein 2) (Phosphodiesterase 4D-interacting protein)
Gene: PDE4DIP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 747 Hs			1 2346
+	Hs
		1138345 PKP3_HUMAN (22-731): 5.23e-109: 352: 24.44		MYOME_HUMAN (1-2346): 0: 703: 100.00
+	Hs
		542356 PLAK_HUMAN (36-727): 2.97e-106: 343: 14.33		MYOME_HUMAN (1-2346): 0: 703: 100.00
+	Mm
		1148448 PKP4_MOUSE (19-745): 6.51e-133: 424: 25.76		MYOME_MOUSE (1-2346): 2.71e-171: 585: 69.33
+	Mm
		970148 CTNB1_MOUSE (522-740): 5.42e-12: 71.6: 12.67		MYOME_MOUSE (1-2346): 2.71e-171: 585: 69.33
+	Hs
		551698 PKP1_HUMAN (1-747): 0: 586: 100.00		DESP_HUMAN (6-681): 6.09e-10: 67.4: 20.72
+	Hs
		1307369 PKP2_HUMAN (6-744): 1.9e-129: 407: 27.50		CP250_HUMAN (682-2334): 3.75e-54: 212: 9.73
+	Hs
		551814 PKP4_HUMAN (19-745): 3.19e-131: 420: 25.63		DESP_HUMAN (6-681): 6.09e-10: 67.4: 20.72
+	Hs
		1307367 PKP2_HUMAN (6-744): 1.9e-129: 407: 27.50		AKAP9_HUMAN (196-822): 2.21e-10: 68.9: 11.25
+	Hs
		551819 PKP2_HUMAN (6-744): 1.9e-129: 407: 27.50		DESP_HUMAN (6-681): 6.09e-10: 67.4: 20.72
+	Hs
		1302360 PKP3_HUMAN (22-731): 5.23e-109: 352: 24.44		CK5P2_HUMAN (1-1501): 2.27e-17: 91.6: 8.90
+	Hs
		551876 PKP3_HUMAN (22-731): 5.23e-109: 352: 24.44		DESP_HUMAN (6-681): 6.09e-10: 67.4: 20.72
+	Hs
		542219 PLAK_HUMAN (36-727): 2.97e-106: 343: 14.33		MYH9_HUMAN (1753-2327): 1.1e-12: 76.2: 11.23
+	Mm
		970212 PLAK_MOUSE (36-727): 1.81e-105: 341: 14.19		CE290_MOUSE (1-666): 3.82e-13: 77.7: 10.25
+	Hs
		542168 PLAK_HUMAN (36-727): 2.97e-106: 343: 14.33		DESP_HUMAN (6-681): 6.09e-10: 67.4: 20.72
+	Hs
		64572 IMA3_HUMAN (206-738): 1.83e-43: 166: 12.86		MYH7B_HUMAN (535-1232): 4.83e-10: 67.7: 16.27
+	Hs
		716819 CTNB1_HUMAN (522-740): 4.93e-12: 71.6: 12.67		MYH10_HUMAN (1099-2077): 1.03e-18: 96.2: 11.20
+	Hs
		716818 CTNB1_HUMAN (522-740): 4.93e-12: 71.6: 12.67		MYH9_HUMAN (1753-2327): 1.1e-12: 76.2: 11.23
+	Rn
		88688 CTNB1_RAT (522-740): 6.55e-12: 71.2: 12.67		D3ZQN7_RAT (342-655): 1.92e-11: 72: 23.26