HitPredict

Interactor 1: RUNX2 (Q13950)
Runt-related transcription factor 2 (Acute myeloid leukemia 3 protein) (Core-binding factor subunit alpha-1) (CBF-alpha-1) (Oncogene AML-3) (Osteoblast-specific transcription factor 2) (OSF-2) (Polyomavirus enhancer-binding protein 2 alpha A subunit) (PEA2-alpha A) (PEBP2-alpha A) (SL3-3 enhancer factor 1 alpha A subunit) (SL3/AKV core-binding factor alpha A subunit)
Gene: RUNX2

Interactor 2: FBW12 (Q6X9E4)
F-box/WD repeat-containing protein 12 (F-box and WD-40 domain-containing protein 12) (F-box only protein 35)
Gene: FBXW12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 521 Hs			1 464
+	Hs
		964358 RUNX1_HUMAN (20-521): 0: 543: 59.22		FBW12_HUMAN (1-464): 0: 732: 100.00
+	Hs
		1045128 RUNX3_HUMAN (20-521): 1.48e-166: 479: 48.83		FBW12_HUMAN (1-464): 0: 732: 100.00