HitPredict

Interactor 1: NOTC2 (Q04721)
Neurogenic locus notch homolog protein 2 (Notch 2) (hN2) [Cleaved into: Notch 2 extracellular truncation (N2ECD); Notch 2 intracellular domain (N2ICD)]
Gene: NOTCH2

Interactor 2: Z354C (Q86Y25)
Zinc finger protein 354C (Kidney, ischemia, and developmentally-regulated protein 3) (hKID3)
Gene: ZNF354C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 2471 Hs			1 554
+	Hs
		599953 NOTC2_HUMAN (22-2471): 0: 1400: 100.00		ZN708_HUMAN (10-553): 0: 713: 43.57
+	Hs
		295027 NOTC2_HUMAN (22-2471): 0: 1400: 100.00		ZN189_HUMAN (60-463): 5.7e-165: 484: 37.47
+	Hs
		1044409 NOTC2_HUMAN (22-2471): 0: 1400: 100.00		ZNF92_HUMAN (60-429): 4.06e-145: 432: 35.82
+	Hs
		275438 NOTC2_HUMAN (22-2471): 0: 1400: 100.00		Z780A_HUMAN (60-382): 1.25e-118: 365: 33.75
+	Hs
		1047667 NOTC2_HUMAN (22-2471): 0: 1400: 100.00		ZN480_HUMAN (150-408): 1.96e-78: 258: 51.74
+	Hs
		71007 NOTC2_HUMAN (22-2471): 0: 1400: 100.00		ZN724_HUMAN (59-189): 6.76e-20: 95.5: 11.36
+	Hs
		1047764 NOTC2_HUMAN (22-2471): 0: 1400: 100.00		ZN624_HUMAN (59-185): 1.03e-18: 92: 9.45
+	Hs
		1047661 NOTC2_HUMAN (22-2471): 0: 1400: 100.00		ZN431_HUMAN (62-185): 2.16e-14: 77.8: 10.40
+	Hs
		1047742 NOTC2_HUMAN (22-2471): 0: 1400: 100.00		ZN430_HUMAN (59-185): 3.65e-12: 70.8: 9.45
+	Hs
		585113 ANR50_HUMAN (1627-2464): 5.06e-117: 410: 14.38		ZN250_HUMAN (1-546): 0: 673: 42.83
+	Hs
		274061 ANR17_HUMAN (1801-2469): 2.56e-69: 262: 17.34		Z780A_HUMAN (60-382): 1.25e-118: 365: 33.75
+	Hs
		1311335 ANKH1_HUMAN (1561-1903): 7.52e-30: 133: 10.28		ZNF34_HUMAN (1-521): 2.87e-140: 419: 44.53
+	Hs
		275444 ANKH1_HUMAN (1561-1903): 7.52e-30: 133: 10.28		Z780A_HUMAN (60-382): 1.25e-118: 365: 33.75
+	Hs
		857467 NOTC1_HUMAN (1094-1611): 2.67e-43: 177: 23.26		ZNF74_HUMAN (144-299): 8.04e-23: 104: 37.18
+	Hs
		1159281 JAG2_HUMAN (1175-1557): 7.17e-27: 122: 22.70		ZNF74_HUMAN (144-299): 8.04e-23: 104: 37.18
+	Hs
		772314 FBN2_HUMAN (1091-1658): 7.87e-11: 70.3: 13.74		ZNF74_HUMAN (144-299): 8.04e-23: 104: 37.18
+	Hs
		1159279 NOTC3_HUMAN (1931-2471): 1.32e-10: 69.6: 16.28		ZNF74_HUMAN (144-299): 8.04e-23: 104: 37.18