HitPredict

Interactor 1: LIM7 (G5EC36)
LIM/homeobox protein lim-7
Gene: lim-7

Interactor 2: H2KZU4 (H2KZU4)
NR LBD domain-containing protein
Gene: nhr-21

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	23791784
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 452 Ce			1 450
+	Ce
		104766 LIM7_CAEEL (1-452): 2.45e-91: 286: 100.00		H2KZU3_CAEEL (1-450): 2.08e-118: 355: 98.89
+	Hs
		823708 LHX2_HUMAN (53-435): 3.46e-61: 206: 25.19		NR2C2_HUMAN (22-448): 2.52e-93: 295: 15.50
+	Hs
		525296 LHX2_HUMAN (53-435): 3.46e-61: 206: 25.19		NR2C1_HUMAN (7-448): 1.05e-76: 252: 14.93
+	Ce
		109972 MEC3_CAEEL (6-101): 1.68e-10: 63.9: 14.55		H2KZU4_CAEEL (1-450): 3.37e-123: 367: 100.00
+	Ce
		109948 MEC3_CAEEL (6-101): 1.68e-10: 63.9: 14.55		H2KZU3_CAEEL (1-450): 2.08e-118: 355: 98.89
+	Hs
		369176 PAXI_HUMAN (55-282): 1.94e-29: 122: 16.67		ESR1_HUMAN (4-447): 3.13e-85: 274: 17.56
+	Ce
		106955 LIN11_CAEEL (5-111): 2.98e-19: 91.3: 15.00		NH114_CAEEL (12-443): 6.28e-95: 294: 20.37
+	Hs
		369562 FHL1_HUMAN (32-267): 2.71e-26: 110: 14.46		ESR1_HUMAN (4-447): 3.13e-85: 274: 17.56
+	Hs
		824492 LHX3_HUMAN (22-111): 7.19e-17: 84: 18.45		NR2C2_HUMAN (22-448): 2.52e-93: 295: 15.50
+	Dm
		574876 AWH_DROME (118-342): 2.34e-34: 131: 23.56		TLL_DROME (17-443): 4.69e-76: 246: 16.09
+	Hs
		150502 ABLM1_HUMAN (55-280): 3.73e-21: 98.6: 15.02		ESR1_HUMAN (4-447): 3.13e-85: 274: 17.56
+	Hs
		824253 LHX4_HUMAN (29-111): 3.65e-12: 69.7: 16.67		NR2C2_HUMAN (22-448): 2.52e-93: 295: 15.50
+	Hs
		369306 LMO4_HUMAN (56-172): 5.22e-20: 88.6: 41.67		ESR1_HUMAN (4-447): 3.13e-85: 274: 17.56
+	Ce
		106954 MEC3_CAEEL (6-101): 1.68e-10: 63.9: 14.55		NH114_CAEEL (12-443): 6.28e-95: 294: 20.37
+	Hs
		369297 ISL1_HUMAN (1-111): 5.65e-16: 80.9: 16.67		ESR1_HUMAN (4-447): 3.13e-85: 274: 17.56
+	Hs
		525335 LHX3_HUMAN (22-111): 7.19e-17: 84: 18.45		NR2C1_HUMAN (7-448): 1.05e-76: 252: 14.93
+	Hs
		525328 LHX4_HUMAN (29-111): 3.65e-12: 69.7: 16.67		NR2C1_HUMAN (7-448): 1.05e-76: 252: 14.93
+	Ce
		589697 LIN11_CAEEL (5-111): 2.98e-19: 91.3: 15.00		Q86PI8_CAEEL (12-316): 1.56e-67: 219: 24.26
+	Ce
		106921 MEC3_CAEEL (6-101): 1.68e-10: 63.9: 14.55		G5EEL3_CAEEL (20-442): 2.54e-76: 245: 17.81
+	Hs
		782510 ISL1_HUMAN (1-111): 5.65e-16: 80.9: 16.67		HNF4A_HUMAN (12-113): 2.93e-27: 115: 49.07