HitPredict

Interactor 1: CSTF1 (Q05048)
Cleavage stimulation factor subunit 1 (CF-1 50 kDa subunit) (Cleavage stimulation factor 50 kDa subunit) (CSTF 50 kDa subunit) (CstF-50)
Gene: CSTF1

Interactor 2: A16L1 (Q676U5)
Autophagy-related protein 16-1 (APG16-like 1)
Gene: ATG16L1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.80	0.659

Property	Details
Experiments	30196744, 31015422
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	WD40~WD40
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 431 Hs			1 607
+	Hs
		845316 LIS1_HUMAN (136-429): 5.55e-74: 238: 19.81		A16L1_HUMAN (1-607): 2.11e-166: 489: 100.00
+	Hs
		1227562 NLE1_HUMAN (247-429): 1.32e-44: 163: 17.94		A16L1_HUMAN (1-607): 2.11e-166: 489: 100.00
+	Sp
		1068482 TUP11_SCHPO (143-429): 6.89e-66: 223: 19.54		TUP11_SCHPO (24-522): 3.24e-70: 239: 13.97
+	Mm
		1297804 CSTF1_MOUSE (1-431): 1.41e-106: 323: 99.54		A16L1_MOUSE (436-605): 1.39e-26: 116: 15.25
+	Hs
		845264 LIS1_HUMAN (136-429): 5.55e-74: 238: 19.81		WDR5_HUMAN (177-474): 3.11e-58: 200: 17.43
+	Hs
		845250 LIS1_HUMAN (136-429): 5.55e-74: 238: 19.81		LIS1_HUMAN (99-438): 4.66e-48: 175: 14.72
+	Mm
		988931 LIS1_MOUSE (136-429): 3.86e-74: 239: 19.81		LIS1_MOUSE (99-438): 1.04e-47: 174: 14.72
+	Hs
		965151 WDR5_HUMAN (2-289): 3.32e-58: 195: 17.75		SNR40_HUMAN (175-514): 4.64e-64: 216: 16.81
+	Hs
		964797 WDR5_HUMAN (2-289): 3.32e-58: 195: 17.75		WDR5_HUMAN (177-474): 3.11e-58: 200: 17.43
+	Hs
		965276 WDR5_HUMAN (2-289): 3.32e-58: 195: 17.75		NLE1_HUMAN (441-607): 8.65e-43: 162: 20.34
+	Hs
		984306 NLE1_HUMAN (247-429): 1.32e-44: 163: 17.94		GBB2_HUMAN (164-516): 1.54e-55: 193: 16.30
+	Sp
		1068486 TUP11_SCHPO (143-429): 6.89e-66: 223: 19.54		TUP12_SCHPO (196-397): 1.71e-29: 125: 12.82
+	Hs
		261437 TBL1Y_HUMAN (11-335): 2.42e-69: 230: 13.50		TBL1X_HUMAN (468-607): 8.64e-25: 110: 19.87
+	Hs
		1410246 TBL1Y_HUMAN (11-335): 2.42e-69: 230: 13.50		TBL1R_HUMAN (479-607): 3.68e-24: 108: 18.71
+	Hs
		1450936 NLE1_HUMAN (247-429): 1.32e-44: 163: 17.94		NLE1_HUMAN (441-607): 8.65e-43: 162: 20.34
+	Hs
		261440 TBL1R_HUMAN (4-293): 1.35e-52: 185: 12.98		TBL1X_HUMAN (468-607): 8.64e-25: 110: 19.87
+	Hs
		965071 WDR5_HUMAN (2-289): 3.32e-58: 195: 17.75		WDR5B_HUMAN (174-393): 1.14e-21: 98.2: 12.96